Gene Therapy for Neurological Disorders

1. Auflage 2006
ISBN: 978-0-8247-2847-2
Verlag: CRC Press

Buch, Englisch, 382 Seiten, Format (B × H): 178 mm x 254 mm, Gewicht: 884 g

Coedited by internationally recognized leaders in gene therapy research, this guide supplies the most recent advances, studies, and expert opinion on gene therapy for neurological disorders. Spanning conditions such as Parkinsons's and Alzheimer's disease, multiple sclerosis, brain tumors, stroke, epilepsy, and brain and spinal cord trauma, this reference presents the basic science and applications of recombinant gene products, immune and stem cell-mediated therapeutic strategies, and brain tumor gene therapy.

Zielgruppe

Professional and Professional Practice & Development

Autoren/Hrsg.

Lowenstein, Pedro R.

Castro, Maria G.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Gentherapie
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

Immune Responses to Viral Vectors: Implications for Neurological Gene Therapy. Gene Transfer to the Nerve System Using HSV-1-Derived Amplicon Vectors. Adeno Associated Viral Vectors for the Nervous System. Heat Shock Proteins for Neurological Gene Therapy. iBAC Technologies for Neurological Disease. Targeted Gene Modification of the Nervous System. Astrocytes as Targets for Neurological Gene Therapy. Targeting Non-Viral Gene Transfer Vectors: What We Learn From Viruses & Other Pathogens. Gene Therapy Applications for Parkinson's Disease. HSV-Mediated Gene Transfer in the Treatment of Chronic Pain. Immunotherapeutic Approaches for Alzheimer's Disease. Gene Therapy of Multiple Sclerosis and in CNS Autoimmune Mouse Models. Novel Gene Therapeutic Approaches to Brain Cancer. Vaccines and Beneficial Immunity in Glioma Patients. Replicating Viruses for Brain Tumor Treatment. Adenovirus-mediated HSV-tk Gene Therapy for Malignant Glioma: Clinical Experience

Über Autor(innen)

Pedro R. Lowenstein, Maria G. Castro