Molecular Pathology of Neoplastic Gastrointestinal Diseases

1. Auflage 2013
ISBN: 978-1-4614-6014-5
Verlag: Springer

Buch, Englisch, Band 7, 277 Seiten, Format (B × H): 215 mm x 285 mm, Gewicht: 8884 g

Reihe: Molecular Pathology Library

Molecular Pathology of Neoplastic Gastrointestinal Diseases   reviews the molecular aspects that characterize the spectrum of neoplastic conditions that affect the gastrointestinal tract, providing the reader with current up-to-date knowledge. For each disease entity chapters provide reviews on:

• the molecular basis of the individual disease
• molecular testing approaches currently available or in development for diagnosis or for gene target characterization for selective targeted therapies
• recommended guidelines for clinical application of molecular tests are included whenever available
• molecular testing for hereditary predisposition or disease risk
• animal models and cell culture models of disease 

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Sepulveda, Antonia R.

Lynch, John P.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Gastroentereologie, Proktologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie

Inhaltsverzeichnis

Section 1. Introduction.- 1. Mechanisms of Gastrointestinal Carcinogenesis.- Section 2. Epithelial Neoplastic Disease.- 2. Targeted Therapies and Molecular Diagnostics of Gastrointestinal Cancers.- 3. Molecular Pathology of Barrett's Metaplasia and Esophageal Adenocarcinoma.- 4. Molecular Pathology of Squamous Carcinomas of the Esophagus.- 5. Molecular Mechanisms and Pathology of Gastric Carcinogenesis: Sporadic Cancers.- 6. Hereditary Diffuse Gastric Cancer and Other Gastric Cancers Associated with Hereditary Predisposition Syndromes.- 7. Cancer Predisposition Syndromes of the Gastrointestinal Tract.- 8. Molecular Pathology of Colon and Small Bowel Cancers: Sporadic Types.- 9. Cancers of the Rectum and Anal Canal.- 10. Molecular Pathology of Inflammatory Bowel Disease Associated Neoplasia.- Section 3. Non-Epithelial Neoplastic  Tumors.- 11. Molecular Biology and Pathology of Gastrointestinal Stromal Tumors.- 12. Neuroendocrine Tumors .- Section 4. Metastatic Disease and Tumor Markers.- 13. Molecular Mechanisms of Tumor Metastases.- 14. Circulating Tumor Cells and Nucleic Acids for Tumor Diagnosis.- 15. Serological Markers of Digestive Tract Cancers.