Tobacco-Specific N-Nitrosamines Recent Advances

1. Auflage 2019
ISBN: 978-0-367-44857-8
Verlag: CRC Press

Buch, Englisch, 140 Seiten, Format (B × H): 210 mm x 280 mm, Gewicht: 362 g

This remarkable book provides updates on various aspects of tobacco - its chemical and biological nature, and its physiological effects.

Zielgruppe

Academic and Professional Practice & Development

Autoren/Hrsg.

McClellan, Roger O.

Fachgebiete

• Geowissenschaften Umweltwissenschaften Umweltwissenschaften
• Naturwissenschaften Chemie Chemie Allgemein
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

1. Introduction 2. Formation and Analysis of Tobacco-Specific N-Nitrosamines 3. Synthesis of Tobacco-Specific N-Nitrosamines and Their Metabolites and Results of Related Bioassays 4. Endogenous Formation of Nitrosamines and Oxidative DNA-Damaging Agents in Tobacco Users 5. Recent Studies on Mechanisms of Bioactivation and Detoxification of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK), A Tobacco-Specific Lung Carcinogen 6. Epidemiology of Cancer by Tobacco Products and the Significance of TSNA 7. The Biological Significance of Tobacco-Specific N-Nitrosamines: Smoking and Adenocarcinoma of the Lung 8. Comparative Carcinogenicity, Metabolism, Mutagenicity, and DNA Binding of 7H-Dibenzo[c,g]carhazole and Dibenz[a,j]acridine 9. Concluding Remarks

Über Autor(innen)

McClellan, Roger O.