Cross-Coupling Reactions

A Practical Guide
1. Auflage. Softcover version of original hardcover Auflage 2002
ISBN: 978-3-642-07576-6
Verlag: Springer

Buch, Englisch, Band 219, 248 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 400 g

Reihe: Topics in Current Chemistry

In 1972, a very powerful catalytic cycle for carbon-carbon bond formation was 2 first discovered by the coupling reaction of Grignard reagents at the sp -carbon. Over the past 30 years, the protocol has been substantially improved and expanded to other coupling reactions of Li,B,N,O,Al,Si,P,S,Cu,Mn,Zn,In,Sn, and Hg compounds. These reactions provided an indispensable and simple methodology for preparative organic chemists. Due to the simplicity and rel- bility in the carbon-carbon, carbon-heteroatom, and carbon-metalloid bo- formations,as well as high efficiency of the catalytic process,the reactions have been widely employed by organic chemists in various fields. Application of the protocol ranges from various syntheses of complex natural products to the preparation of biologically relevant molecules including drugs, and of sup- molecules, and to functional materials. The reactions on solid surfaces allow robot synthesis and combinatorial synthesis. Now, many organic chemists do not hesitate to use transition metal complexes for the transformation of org- ic molecules. Indeed, innumerable organic syntheses have been realized by the catalyzed reactions of transition metal complexes that are not achievable by t- ditional synthetic methods. Among these, the metal-catalyzed cross-coupling reactions have undoubtedly contributed greatly to the development of such a new area of “metal-catalyzed organic syntheses”. An excellent monograph for the cross-coupling reactions and other met- catalyzed C-C bond-forming reactions recently appeared in Metal-catalyzed Cross-coupling Reactions (Wiley-VCH,1998).

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Miyaura, Norio

Weitere Mitwirkende

Buchwald, S.L.

Fugami, K.

Hiyama, T.

Kosugi, M.

Miura, M.

Miyaura, N.

Muci, A.R.

Nomura, M.

Shirakawa, E.

Tamao, K.

Fachgebiete

• Naturwissenschaften Chemie Physikalische Chemie Elektrochemie, Magnetochemie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Verfahrenstechnik, Chemieingenieurwesen
• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde Werkstoffkunde, Materialwissenschaft: Forschungsmethoden
• Naturwissenschaften Chemie Organische Chemie Organometallchemie

Inhaltsverzeichnis

to Cross-Coupling Reactions.- Organoboron Compounds.- Organosilicon Compounds.- Organotin Compounds.- Practical Palladium Catalysts for C-N and C-O Bond Formation.- Direct Arylation via Cleavage of Activated and Unactivated C-H Bonds.