Glycoproteins I

Erscheinungsjahr 1995
ISBN: 978-0-444-82075-4
Verlag: Elsevier BV

Buch, Englisch, 640 Seiten, Format (B × H): 156 mm x 234 mm, Gewicht: 1240 g

Part I covers modern advances in the determination ofglycoprotein structure and in the biosynthesis of mammalian,bacterial, yeast, plant and insect glycoproteins. There are alsotwo chapters on functional aspects (glycoprotein hormones andcollagens).The content of the volume is very comprehensive in that, mostcontributors have focussed on discussing, in depth, the wealthof most recent advances in their field, and referring to previousreviews of older work for background information. This method caneffectively produce a very wide subject coverage in a smallernumber of chapters/volumes.The volume is an importantinformation source for all glycobiologist researchers (seniorinvestigators, post-doctoral fellows and graduate students), andas a good, comprehensive, reference text for scientists working inthe life sciences.

Autoren/Hrsg.

Montreuil, J.

Vliegenthart, J.F.G.

Schachter, H.

Fachgebiete

• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Proteinforschung

Inhaltsverzeichnis

Part I: Preface (A. Neuberger). Chapter 1: History of glycoprotein research (J. Montreuil). Chapter 2: Primary Structure of glycoprotein glycans (J.F.G. Vliegenthart, J. Montreuil). Chapter 3: 3D-Structure: The structured features of protein-carbohydrate interactions revealed by X-ray crystallography (C. Cambillau). Three dimensional structure of oligosaccharides explored by -NMR and computer calculations (S.W. Homans). Chapter 4: Chemical Synthesis of Glycopeptides (H. Paulsen, S. Peters, T. Bielfeldt). Chapter 5: Biosynthesis Introduction (H. Schachter), The coenzymatic role of phosphodolichols (F. Hemming), From Glc3Man9GlcNAc2-protein to Man5GlcNAc2-protein: transfer 'en bloc' and processing (A. Verbert), Glycosyltransferases involved in the synthesis of N-glycan antennae (H. Schachter), Biosynthesis of O-glycans of the N-acetylgalactosamine-&agr;-Ser/Thr linkage type (I. Brockhausen), Gene regulation of terminal glycosylation (M.C. Glick), Substrate level controls for N-glycan assembley (H. Schachter), Compartmentation of glycoprotein biosynthesis (J. Roth), Molecular basis of antigenic specificity in the ABO, H and Lewis blood-group systems (W.M. Watkins), The role of polypeptide in the biosynthesis of protein-linked oligosaccharides (R.T. Camphausen, H-A. Yu and D.A. Cumming), How can N-linked glycosylation and processing inhibitors be used to study carbohydrate synthesis and function? (Y.T. Pan and A.D. Elbein). Chapter 6: Bacterial Glycoproteins (M. Sumper, F.T. Wieland). Chapter 7: Protein Glycosylation in Yeast (L. Lehle, W. Tanner). Chapter 8: O-Glycosylation in Plants (F.M. Klis). Chapter 9: N-Glycosylation of plant proteins (A. Sturm). Chapter 10: Protein Glycosylation in Insects (L. März, F. Altmann, E. Staudacher, V. Kubelka). Chapter 11: The Glycoprotein Hormone Family (M. Bielinska and I. Boime). Chapter 12: Carbohydrate Moiety of Vertebrate Collagens (M.E. Noelken and B.G. Hudson).