Miniaturised Mass Spectrometry

1. Auflage 2027
ISBN: 978-1-83767-621-7
Verlag: Royal Society of Chemistry

Buch, Englisch, 446 Seiten, Format (B × H): 156 mm x 234 mm, Gewicht: 650 g

From towering instruments the size of cupboards to compact devices pushing the frontiers of modern science, the evolution of mass spectrometry has been nothing short of revolutionary. Once confined to the analytical chemist’s lab, mass spectrometers are now finding their place in diverse environments – from clinical diagnostics and environmental monitoring to space exploration – all thanks to the remarkable advance of miniaturisation.

This book offers a comprehensive journey through the past three decades of innovation in miniaturised mass spectrometry. Beginning with a clear introduction to the principles and purpose of mass spectrometry, it takes readers deep into the engineering challenges, design considerations and functionality of various compact models including single quadrupoles, ion traps and time-of-flight systems. With rich theoretical insight and application-based case studies spanning forensic science, pharmaceuticals and hazardous settings, this is an indispensable guide for both newcomers and seasoned professionals.

Packed with expert commentary and visionary perspectives, it lays the groundwork for the future of portable analytical tools and the ever-expanding reach of this once-specialised technology.

Autoren/Hrsg.

Moseley, Richard W

Fachgebiete

• Interdisziplinäres Wissenschaften Wissenschaften: Forschung und Information Forschungsmethodik, Wissenschaftliche Ausstattung
• Naturwissenschaften Chemie Analytische Chemie Massenspektrometrie, Spektroskopie, Spektrochemie

Inhaltsverzeichnis

- Introduction

- History of Mass Spectrometry and Its Miniaturisation

- Vacuum and Front-end Ionisation Source Considerations for a Miniaturised Mass Spectrometer

- Design and Development of a Miniaturised Single Quadrupole Mass Spectrometer

- Development of a Miniaturised Ion Trap Mass Spectrometer

- Development of a Miniaturised MALDI-TOF Mass Spectrometer

- Use of Miniaturised Mass Spectrometry in Forensic Testing

- Miniaturised Mass Spectrometry in the Pharmaceutical Industry and Process Analytical Technologies (PAT)

- The Use of Miniaturised Mass Spectrometry in Clinical and Point-of-care Testing

- Use of Miniaturised and Field-deployable Mass Spectrometry for Environmental Monitoring

- Use of Miniaturised Mass Spectrometry in Hazardous Environments

- Challenges and Future Developments of Miniaturised Mass Spectrometry