Alzheimer's Disease

Understanding Biomarkers, Big Data, and Therapy
Erscheinungsjahr 2021
ISBN: 978-0-12-821334-6
Verlag: William Andrew Publishing

Buch, Englisch, 254 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 410 g

Nearly 44 million people have Alzheimer's or related dementia worldwide, according to the Alzheimer's Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Alzheimer's Disease: Understanding Biomarkers, Big Data, and Therapy covers recent advancements in cognitive, clinical, neural, and therapeutic aspects of Alzheimer's and other forms of dementia.

First, readers are introduced to cognitive and clinical studies, focusing on the different types of memory impairment, past and future thinking. This includes the prevalence of depression, its relationship to other symptoms, and the quality of life for those with Alzheimer's disease. In addition, the book discusses recent studies on memory dysfunction in advanced-stage Alzheimer's disease, in comparison to early-stage, including a chapter on the underlying factors in the transition from mild cognitive impairment to Alzheimer's diagnosis. Following this section, the book presents recent studies on the role of different cortical and subcortical structures in the development of various symptoms in Alzheimer's disease, as well as different neural biomarkers underlying the development and treatment of the disease. In the last section of the book, therapeutic aspects of Alzheimer's disease, focusing on behavioral and pharmacological treatments of sleep disorders, memory problems, and depression, are reviewed. The book aids readers in understanding the advances in research and care, making it a prime tool for all clinicians, psychologists, researchers, neurologists, and caregivers of dementia patients.

Zielgruppe

Advanced students and researchers in cognitive and behavioral neuroscience, psychology, psychiatry, psychotherapy, neurology

Autoren/Hrsg.

Moustafa, Ahmed

Fachgebiete

• Sozialwissenschaften Psychologie Psychotherapie / Klinische Psychologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Alzheimer und Demenz
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft

Inhaltsverzeichnis

Part I: Mental Health in Dementia

1. Measures of depression in Alzheimer's disease

Ahmed A. Moustafa, Wafa Jaroudi, Lily Bilson and Mohamad El Haj

2. The nature of depression in dementia: A narrative review

Ahmed A. Moustafa, Phoebe Bailey, Wafa Jaroudi, Lily Bilson and Mohamad El Haj

3. Stress and anxiety in dementia

Ahmed A. Moustafa, Shimaa Adel Heikal and Wafa Jaroudi

Part II: Advanced Topics in Dementia Research

4. Alzheimer's disease in the pupil: Pupillometry as a biomarker of cognitive processing in Alzheimer's Disease

Ahmed A. Moustafa and Mohamad El Haj

5. Cognitive and neural correlates of vitamin D deficiency: Focus on healthy aging and Alzheimer's Disease

Ahmed A. Moustafa, Wafa Jaroudi and Abdrabo Soliman

6. The effect of Alzheimer's Disease on the thalamus

Ahmed A. Moustafa and Rasu Karki

7. Using big data methods to understand Alzheimer's Disease

Ahmed A. Moustafa, Samuel L. Warren and Hany Alashwal

8. Operational aspects of deep learning solutions for Alzheimer's Disease

Ahmed A. Moustafa, Dustin van der Haar and Samuel L. Warren

Part III: Treatment of Dementia

9. Treatment of depression in Alzheimer's Disease

Ahmed A. Moustafa, Lily Bilson and Wafa Jaroudi

10. Developing a vulnerability to negative affect scale for music interventions for people with dementia

Ahmed A. Moustafa, Sandra Garrido and Wafa Jaroudi

11. Using music to improve mental health in people with dementia

Ahmed A. Moustafa, Wafa Jaroudi and Sandra Garrido

12. The efficacy of Donepezil for the treatment of Alzheimer's Disease

Ahmed A. Moustafa and Samuel L. Warren

Über Autor(innen)

Moustafa, Ahmed
Dr. Ahmed Moustafa is the Head of School of Psychology and Professor of Psychology and Computational Modeling at Bond University, Australia. He obtained his BSc in Mathematics and Computer Science at Cairo University, Egypt, and his PhD in Cognitive Science at the University of Lafayette, USA. Dr. Moustafa specializes in computational and neuropsychological studies of addiction, schizophrenia, Parkinson's disease, PTSD, depression, and Alzheimer's disease. He is the Editor-in-Chief of Discover Psychology (Springer) and has edited ten books, including Elsevier's Cognitive, Clinical, and Neural Aspects of Drug Addiction; The Psychology and Neuroscience of Impulsivity; Cognitive and Behavioral Dysfunction in Schizophrenia; Mental Health Effects of COVID-19; Alzheimer's Disease; Cybersecurity and Cognitive Science; Big Data in Psychiatry and Neurology; The Nature of Depression; and Social Cognition in Psychosis.