Medical Applications of iPS Cells

Innovation in Medical Sciences
1. Auflage 2019
ISBN: 978-981-13-3671-3
Verlag: Springer Nature Singapore

Buch, Englisch, 190 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 507 g

Reihe: Current Human Cell Research and Applications

This volume highlights recent advances using iPS cells in disease modeling and medical applications along with new technologies that enhance the power of iPS cells. While the discovery of iPS cells has provided excellent opportunities for developing models of human diseases, platforms for drug discovery and cell therapies, iPS cell technology still faces many challenges. Presenting the latest advances in this rapidly evolving research area, this book is intended to widen the community of researchers and clinicians interested in the exciting field of iPS cells.

Zielgruppe

Research

Autoren/Hrsg.

Nakamura, Yukio

Inoue, Haruhisa

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

Introduction. Overview.- Disease Modeling. iPSCs for disease modeling.- Reprogramming cancer cells.- Recapitulating hematopoiesis in the lab.- Modeling cardiomyopathies with iPSCs.- Molecular Technologies. Controling cell state with intracellular biomarkers.- Genome editing of stem cells.- iPS Applications. iPSC-based cell therapy for eye diseases.- 3D models for organ development.- Drug discovery using iPSCs.- Direct differentiation of neural cells.

Über Autor(innen)

Haruhisa Inoue, CiRA, Kyoto University, Japan; RIKEN BRC, Japan; RIKEN AIP, JAPAN
Yukio Nakamura, RIKEN BioResource Center, Japan