Structure and Function in Organic Cocrystals: Design, Crystal Array and Stimuli-Response

Erscheinungsjahr 2027
ISBN: 978-3-032-46250-3
Verlag: Springer

Buch, Englisch, 182 Seiten, Format (B × H): 155 mm x 235 mm

Reihe: Springer Theses

This book provides an integrated experimental perspective on the design and understanding of photophysical responses in organic cocrystals by integrating molecular design, non-covalent interactions, and internal molecular dynamics. Through the deliberate construction of donor–acceptor and hydrogen-bonded architectures, this book demonstrates how mobile molecular fragments (particularly fluorinated acceptors) interact with the surrounding crystalline environment to modulate charge transfer, non-radiative relaxation pathways, and emission behavior. Structural elucidation, solid-state spectroscopy, and thermodynamic analyses reveal that rotational and vibrational motions are not passive byproducts of crystal packing, but rather tunable features that directly influence photothermal conversion, fluorescence efficiency, light propagation, and mechanical responsiveness. The thesis further shows that modifying the distribution and anisotropy of interaction energies offers a powerful strategy to switch between regenerative, reversible responses and irreversible, mechanically active behaviors such as thermosalience. Altogether, this book provides experimentally grounded design principles for engineering responsive molecular solids, demonstrating that the interplay between dynamic fragments and supramolecular organization can be harnessed to create functional materials with tunable optical and mechanical properties or controllable stimuli-responsive properties.

Zielgruppe

Research

Autoren/Hrsg.

Navarro Huerta, Armando

Fachgebiete

• Naturwissenschaften Chemie Organische Chemie
• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde
• Technische Wissenschaften Technik Allgemein Nanotechnologie

Inhaltsverzeichnis

General Introduction to Crystal Engineering.- Characterization Techniques.- The In-plane Rotational Dynamics of a Fluorinated Acceptor and its Influence on the Photothermal Conversion Efficiency.- Modulation of the Rotational Dynamics of a Fluorinated Acceptor: The Donor-Variation Strategy and Transition State Theory.- Modulation of the Photoluminescence in Optical Waveguiding Cocrystals: Mobile and Static Acceptor.- Modulation of the Photoluminescence Through Changes in the Crystallinity of Hydrogen-Bonded Cocrystals.- Conclusions.

Über Autor(innen)

Dr. Armando Navarro Huerta obtained his B.Sc. (2019), M.Sc. (2021), and Ph.D. in Science (2026) from the Universidad Nacional Autónoma de México (UNAM), conducting his doctoral research at the Instituto de Química under the supervision of Prof. Braulio Rodríguez Molina. His research focuses on crystal engineering, molecular dynamics, and structure–property relationships in functional organic crystals and cocrystals, particularly their photophysical and stimuli-responsive behavior. Following his doctoral studies, he worked as a Global Clinical Trial Associate at ICON plc, gaining experience in clinical research operations. Since September 2026, he has been a postdoctoral researcher at the Université Libre de Bruxelles (ULB), Belgium, under the supervision of Prof. Yves Geerts, investigating polymorphism, crystallization, and solid-state phase behavior of pharmaceutical compounds. His scientific contributions include peer-reviewed publications, a book chapter on carbazole-derived materials, and presentations at international conferences. He received the Young Lectureship Award from the Mexican Academy of Organic Chemistry.