Navigating the Complexities of SARS-CoV-2 Immunobiology

Erscheinungsjahr 2025
ISBN: 978-0-443-23832-1
Verlag: Elsevier Inc

Buch, Englisch, 476 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 804 g

Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.

Autoren/Hrsg.

Weitere Mitwirkende

Uversky, Vladimir N.

Hromic-Jahjefendic, Altijana

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

Preface
Vladimir N. Uversky and Altijana Hromic Jahjefendic
1. T cell immunobiology and cytokine storm of COVID-19
Elrashdy Moustafa REDWAN
2. Analysis of the immune response in COVID-19
Altijana Hromic Jahjefendic
3. Immunobiology and immunotherapy of COVID-19
Kenneth Lundstrom
4. COVID-19: Immunology and treatment options
Giorgio Palu
5. Type I interferon, anti-interferon antibodies, and COVID-19
Jasmin Mušanovic
6. COVID-19: perspectives on innate immune evasion
Alaa A A Aljabali, Mohamed El-Tanani, Debmalya Barh and Murtaza M. Tambuwala
7. Impact of COVID-19 on preexisting comorbidities
Elrashdy Moustafa REDWAN
8. COVID-19 related complications including long COVID
Nicolas G. Bazan
9. COVID-19 and IgG4
10. The intersection of COVID-19 and autoimmunity
11. Neutrophils and COVID-19
12. Immunobiology of long COVID

Über Autor(innen)

Uversky, Vladimir N.
Prof. Vladimir N. Uversky, PhD, DSc, FRSB, FRSC, F.A.I.M.B.E., Professor at the Department of Molecular Medicine, Morsani College of Medicine, University of South Florida (USF), is a pioneer in the field of protein intrinsic disorder. He has made a number of groundbreaking contributions in the field of protein folding, misfolding, and intrinsic disorder. He obtained his PhD from Moscow Institute of Physics and Technology and D.Sc. from the Institute of Experimental and Theoretical Biophysics, Russian Academy of Sciences. Since 2010, Professor Uversky has worked at University of South Florida, where he works on various aspects of protein intrinsic disorder phenomenon and analysis of protein folding and misfolding processes. He has authored over 1250 scientific publications and edited several books and book series on protein structure, function, folding, misfolding, and intrinsic disorder. He also servs as an editor in a number of scientific journals.

Hromic-Jahjefendic, Altijana
Prof. Dr. Altijana Hromic-Jahjefendic, PhD, Professor at the Department of Genetics and Bioengineering, International University of Sarajevo. She obtained her academic degrees from University of Graz, Austria (PhD degree in 2017 in protein biochemistry) and from Graz University of Technology, Austria (MSc degree in 2013 in protein biochemistry). After obtaining her PhD degree, she returned to her home country, Bosnia and Herzegovina, and started to work at International University of Sarajevo on lymphoma research. As a young researcher, she started collaboration with international colleagues authoring many scientific publications in cancer research and COVID-19.