The Dopamine Receptors

2. Auflage 2010
ISBN: 978-1-60327-332-9
Verlag: Humana Press

Buch, Englisch, 648 Seiten, HC runder Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 1265 g

Reihe: The Receptors

As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. Updated from the successful first edition, "The Dopamine Receptors" serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. To achieve this goal, authors have written chapters that set a broad area of research in its historical context, rather than focusing on the research output of their own laboratories.

Zielgruppe

Research

Autoren/Hrsg.

Neve, Kim

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften Neurobiologie, Verhaltensbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Neuropharmakologie, Psychopharmakologie
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Psychiatrie, Sozialpsychiatrie, Suchttherapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

Historical Overview: Introduction to the Dopamine Receptors.- Gene and Promoter Structures of the Dopamine Receptors.- Structural Basis of Dopamine Receptor Activation.- Dopamine Receptor Subtype-Selective Drugs: D1-Like Receptors.- Dopamine Receptor Subtype-Selective Drugs: D2-Like Receptors.- Dopamine Receptor Signaling: Intracellular Pathways to Behavior.- Dopaminergic Modulation of Glutamatergic Signaling in Striatal Medium Spiny Neurons.- Regulation of Dopamine Receptor Trafficking and Responsiveness.- Dopamine Receptor-Interacting Proteins.- Dopamine Receptor Oligomerization.- Dopamine Receptor Modulation of Glutamatergic Neurotransmission.- Unraveling the Role of Dopamine Receptors In Vivo: Lessons from Knockout Mice.- Dopamine Receptors and Behavior: From Psychopharmacology to Mutant Models.- Dopamine Modulation of the Prefrontal Cortex and Cognitive Function.- In Vivo Imaging of Dopamine Receptors.- Dopamine Receptors and the Treatment of Schizophrenia.- Dopamine Receptor Subtypes in Reward and Relapse.- Dopamine Receptors and the Treatment of Parkinson’s Disease.- Dopamine Receptor Genetics in Neuropsychiatric Disorders.