Nieder / Milas / Ang | Modification of Radiation Response | Buch | 978-3-642-62670-8 | www.sack.de

Buch, Englisch, 284 Seiten, Format (B × H): 193 mm x 270 mm, Gewicht: 647 g

Reihe: Medical Radiology

Nieder / Milas / Ang

Modification of Radiation Response

Cytokines, Growth Factors, and Other Biological Targets
Erscheinungsjahr 2012
ISBN: 978-3-642-62670-8
Verlag: Springer

Cytokines, Growth Factors, and Other Biological Targets

Buch, Englisch, 284 Seiten, Format (B × H): 193 mm x 270 mm, Gewicht: 647 g

Reihe: Medical Radiology

ISBN: 978-3-642-62670-8
Verlag: Springer


This book describes and summarizes the radiation responses of both normal and neoplastic tissues with a focus on rational strategies for the modification of these responses. Emerging data from molecular oncology and radiobiology are reviewed in depth. The book covers not only general principles of radiation-induced reactions but also a large number of preclinical and clinical data that will guide the reader through this complex and dynamic field and will provide valuable information for the development of further research projects.

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Zielgruppe


Professional/practitioner

Weitere Infos & Material


I: Normal Tissues.- 1 The Potentional Role of Signaling Proteins in the Acceleration of Repopulating Normal and Malignant Tissues.- 2 Role of Radiation-Induced Signaling Proteins in the Response of Vascular and Connective Tissues.- 3 Pathogenetic Mechanisms of Lung Fibrosis.- 4 Strategies for Modification of the Radiation Response of the Lung.- 5 Mechanisms and Modification of the Radiation Response of Gastrointestinal Organs.- 6 Mechanisms and Modification of the Radiation Response of the Central Nervous System.- 7 Hematopoietic Tissue I: Response Modification by Erythropoietin.- 8 Hematopoietic Tissue II: Role of Colony-Stimulating Factors.- 9 Oral Mucosa: Response Modification by Keratinocyte Growth Factor.- II: Malignancies.- 10 Role of Growth Factors in Tumor Growth and Progression of Gynecological Tumors.- 11 Growth Factor Expression in Central Nervous System Tumours.- 12 Role of Growth Factors and Biological Response Modifiers in Lung, Head and Neck and Gastrointestinal Tumors.- 13 Role of Signaling Pathway Modification.- 14 Anti-VEGF Strategies in Combination with Radiotherapy.- 15 Role of Epidermal Growth Factor Receptor and Its Inhibition in Radiotherapy.- 16 Enhancement of the Radiation Response with Interleukins and Interferons.- 17 Enhancement of Radiation Response with TNF/TRAIL.- 18 Role of Cyclooxygenase-2 (COX-2) and its Inhibition in Tumor Biology and Radiotherapy.- 19 Ras Signaling and Its Inhibition with Farnesyltransferase Inhibitors: Effects on Radiation Resistance and the Tumor Microenvironment.- List of Contributors.



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