Single-molecule Studies of Proteins

2013
ISBN: 978-1-4899-9112-6
Verlag: Springer

Buch, Englisch, Band 2, 274 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 4394 g

Reihe: Biophysics for the Life Sciences

In Single Molecule Studies of Proteins , expert researchers discuss the successful application of single-molecule techniques to a wide range of biological events, such as the imaging and mapping of cell surface receptors, the analysis of the unfolding and folding pathways of single proteins, the analysis interaction forces between biomolecules, the study of enzyme catalysis or the visualization of molecular motors in action. The chapters are aimed at established investigators and post-doctoral researchers in the life sciences wanting to pursue research in the various areas in which single-molecule approaches are important; this volume also remains accessible to advanced graduate students seeking similar research goals.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Oberhauser, Andres F.

Fachgebiete

• Naturwissenschaften Biowissenschaften Proteinforschung
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

Nanomechanics of proteins, both folded and disordered.- Force Spectroscopy and Recognition Imaging of Cells from the Immune System.- Catch bonds of integrin/ligand interactions.- AFM visualization of protein-DNA interactions.- Nano-visualization of proteins in action using high-speed AFM.- Enzyme catalysis at the single-molecule level.- Single-molecule studies of amyloidogenic proteins.- Stretching and Imaging Individual Proteins on Live Cells using Atomic Force Microscopy.- Individual proteins under mechanical stress: Lessons from theory and computer simulations.