Clinical Molecular Diagnostics

1. Auflage 2021
ISBN: 978-981-16-1036-3
Verlag: Springer

Buch, Englisch, 889 Seiten, Format (B × H): 215 mm x 285 mm, Gewicht: 2717 g

This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Pan, Shiyang

Tang, Jinhai

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Labormedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie

Inhaltsverzeichnis

Part 1 Principles of Clinical Molecular Diagnostics.- 1 Molecules of Diseases and Their Detection Methods.- 2 Assay Performance Evaluation.- 3 Establishment of Biological Reference Interval.- 4 Ethics: Informed Consent, Patient Privacy.- 5 Bioinformatics.- 6 Report and Consultation.- 7 Factors Associated with Variation.- 8 Quality Control and Quality Assurance.- 9 Precision Medicine.- Part 2 Molecular Biomarkers and Signals from Diseased Functional Organ.- 10 Molecules in Body Systems.- 11 Molecules in Signal Pathways.- 12 Endocrine and Metabolism.- 13 Immune System.- 14 Lipoproteins.- 15 Transport and Carrier Proteins.- 16 Coagulation and Fibrinolysis.- 17 Cardiovascular System.- 18 Pregnancy.- 19 Urine.- 20 Bone.- 21 Cancer.- 22 Translation Research of Novel Biomarker.- Part 3 Advanced Molecular Diagnostic Techniques.- 23 Next-generation Sequencing (NGS).- 24 Digital PCR.- 25 Biosensor.- 26 Microfluidic Chip.- 27 Liquid Biopsy.- 28 Molecular Targeted Imaging.- 29 Fluorescence in Situ Hybridization.- 30 Circulating DNA Quantification.- 31 DNA Methylation Detection Techniques.- Part 4 Disease Presentation and Clinical Laboratory Procedures.- 32 Immunological Disorders.- 33 Liver Diseases.- 34 Pancreatic Diseases.- 35 Digestive Tract Disease.- 36 Kidney Diseases.- 37 Cardiovascular Disease.- 38 Lung Disease.- 39 Blood Disorders.- 40 Endocrine and Metabolic Diseases.- 41 Neurological Disease.- 42 Reproductive Organ Cancer.- 43 Reproductive Organ Cancer.- 44 Transplant Matching.- 45 Paternity Test.

Über Autor(innen)

Editor Shiyang Pan, M.D, Ph.D., is a chief physician and the director of the Dept. of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Editor Jinhai Tang is a professor at The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.