Spirooxindole

Chemistry, Synthesis, Characterization and Biological Significance
Erscheinungsjahr 2024
ISBN: 978-0-443-22324-2
Verlag: Elsevier Inc

Buch, Englisch, 660 Seiten, Format (B × H): 216 mm x 279 mm, Gewicht: 1506 g

Spirooxindole: Chemistry, Synthesis, Characterization and Biological Significance examines the current state-of-the-art, recent progress, and new challenges associated with the development of spirooxindole derivatives for various medicinal applications. Owing to their exceptional properties, these compounds can be used in various fields, including chemical and pharma industries, and in clinical research. This book has chapters written by experts in several different areas. It serves as a useful reference book for scientists, industrial practitioners, graduate students, and other professionals in the field of hetrocyclic chemistry, medicinal chemistry, organic synthesis clinical research and chemical sciences. The growing interest among the academics and industrial researchers in the field of organic chemistry and medicinal chemistry is the driving force for the presentation of this edited book.

Autoren/Hrsg.

Patel, Gautam

Nguyen, Tuan Anh

Deshmukh, Kalim

Fachgebiete

• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Naturwissenschaften Chemie Organische Chemie

Inhaltsverzeichnis

1. Introduction of Spirooxindole 2. Synthesis of spirooxindole and its derivatives using green and nano technology 3. Stereoselective synthesis of spirooxindole scaffold 4. Characterization techniques for synthesised spirooxindole scaffold 5. Spirooxindole as a precursor 6. Medicinal applications of Spirooxindole and its derivatives- An Introduction 7. Spirooxindole derivatives as an anti-cancer agent 8. Spirooxindole derivatives as kinase based anti-cancer agents 9. Spirooxindole derivatives as an anti-viral agent 10. Spirooxindole derivatives as an anti-bacterial agent 11. Spirooxindole derivatives as an anti-oxidant agent 12. Spirooxindole derivatives as an anti-inflammatory agent 13. Other Medicinal Applications 14. A case study of the use of spirooxindole derivatives in the novel drug discovery

Über Autor(innen)

Patel, Gautam
Gautam Patel obtained PG from Institute of Science and Technology for Advanced Studies and Research (ISTAR), Vallabh Vidya Nagar and Doctoral degree from the M. S. University of Baroda, India. He is the Head and an Associate Professor at the Chemistry Department, Parul Institute of Applied Science, Parul University, India. His area of specialization is organic synthesis, green chemistry, nanosciences and nanotechnology. He has 3 patents to his name.

Nguyen, Tuan Anh
Tuan Anh Nguyen is a Senior Principal Research Scientist at the Institute for Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. He received a BS in physics from Hanoi University in 1992, a BS in economics from Hanoi National Economics University in 1997, and a PhD in chemistry from the Paris Diderot University, France, in 2003. He was a Visiting Scientist at Seoul National University, South Korea, in 2004, and the University of Wollongong, Australia, in 2005. He then worked as a Postdoctoral Research Associate and Research Scientist at Montana State University, United States in 2006-09. In 2012 he was appointed as the Head of the Microanalysis Department at the Institute for Tropical Technology. His research areas of interest include smart sensors, smart networks, smart hospitals, smart cities, complexiverse, and digital twins. He has edited more than 74 books for Elsevier, 12 books for CRC Press, 1 book for Springer, 1 book for RSC, and 2 books for IGI Global. He is the Editor-in-Chief of Kenkyu Journal of Nanotechnology & Nanoscience.

Deshmukh, Kalim
Dr. Kalim Deshmukh is a senior researcher at the New Technologies Research Centre, University of West Bohemia in Pilsen, Czech Republic. He has over 20 years of research experience in nanomaterials and polymeric materials, with particular expertise in polymer blends, nanocomposites, and nanohybrids. His work emphasizes nanoscale dispersion, interfacial chemistry, and structure–property relationships that influence material performance in applications such as energy storage, gas sensing, biosensing, electromagnetic interference (EMI) shielding, and high-k dielectrics. He has authored more than 200 publications, including original research articles and review papers, in leading international journals and with major publishers, such as the Royal Society of Chemistry (RSC), American Chemical Society (ACS), Elsevier, Wiley-VCH, Springer, and Taylor & Francis. In addition to his research contributions, he has edited or co-edited several books published by ACS, RSC, Elsevier, Springer, Wiley-VCH, and Wiley Scrivener.