Buch, Englisch, 512 Seiten, Format (B × H): 245 mm x 172 mm, Gewicht: 984 g
Buch, Englisch, 512 Seiten, Format (B × H): 245 mm x 172 mm, Gewicht: 984 g
ISBN: 978-1-394-26330-1
Verlag: John Wiley & Sons Inc
Primary source for learning pharmaceutical analytical chemistry, fully updated and revised to reflect current practice and Pharmacopoeia standards
Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques, and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products, and drug substances in biological fluids.
Extensively revised throughout to reflect the current European Pharmacopoeia (Ph.Eur) and United States Pharmacopeia (USP), this Third Edition presents updated methodologies, practical examples, and calculations to reflect current pharmaceutical laboratory practice. Revisions to the chapter structure, text, and figures have been implemented to improve clarity and comprehension. New practice problems, up-to-date practical examples, and detailed illustrations are also included throughout the text.
Written by a team of experienced academics, Introduction to Pharmaceutical Analytical Chemistry explores topics including: - Fundamentals of bases, acids, solubility, polarity, partition, stereochemistry, and pharmaceutical analytical chemistry
- Marketing authorizations, pharmaceutical manufacturing, titration, UV-Vis spectrophotometry, IR spectrophotometry, and atomic spectrometry
- Separation principles in liquid chromatography, high-performance liquid chromatography, gas chromatography, electrophoretic methods, and mass spectrometry
- Sample preparation, quality of analytical data and validation, and chemical analysis of pharmaceutical ingredients and preparations
- Bioanalysis chemical analysis of pharmaceuticals in biological fluids and chemical analysis of biopharmaceuticals
Introduction to Pharmaceutical Analytical Chemistry is essential reading for chemists, biochemists, and other scientists entering the pharmaceutical industry, along with undergraduate and graduate students enrolled in pharmaceutical courses.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Preface to the Third Edition xiii
Symbols and Units xv
Chapter 1: The Link Between Pharmaceuticals and Analytical Chemistry 1
Chapter 2: The Link between Pharmaceutical Substances and Pharmacopoeias 15
Chapter 3: Chemical and Physicochemical Properties of Pharmaceutical Substances and Reagents 39
Chapter 4: Fundamentals of Pharmaceutical Analytical Chemistry 59
Chapter 5: Titration 97
Chapter 6: Introduction to Spectroscopic Methods 121
Chapter 7: UV-Vis Spectrophotometry 130
Chapter 8: Infrared Spectrophotometry 150
Chapter 9: Atomic Spectrometry 161
Chapter 10: Introduction to Chromatography 175
Chapter 11: Separation Principles in Liquid Chromatography 190
Chapter 12: High-Performance Liquid Chromatography 215
Chapter 13: Gas Chromatography 230
Chapter 14: Electrophoretic Methods 246
Chapter 15: Mass Spectrometry 262
Chapter 16: Sample Preparation 290
Chapter 17: Data Quality, Quantification and Validation 311
Chapter 18: Chemical Analysis of Pharmaceutical Substances 337
Chapter 19: Chemical Analysis of Pharmaceutical Products 380
Chapter 20: Bioanalysis 415 20.1 Biological Fluids: Composition, Sample Collection and Storage 416
Chapter 21: Chemical Analysis of Biopharmaceuticals 432
Index 469
