Biochemical and Clinical Aspects of Essential Phospholipids
Buch, Englisch, 254 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 468 g
ISBN: 978-3-642-66426-7
Verlag: Springer
A symposium was centered around the unsaturated phosphatidyl choline molecule and organized in order to assemble and coordi nate theoretical views with facts and results. The presence of a high percentage of essential fatty acids in unsaturated phos phatidylcholine gave rise to the essential phospholipid concept. An overview of the biological significance of phospholipids and a review of a specific phosphatidylcholine-related enzyme, namely LCAT or lecithin cholesterol acyl transferase, open these proceedings. The simultaneous use of the synonyms - leci thin and phosphatidylcholine - was solved throughout the pub lished material by a preferential use of the more precise che mical terminology of phosphatidylcholine. A set of papers centered around the pharmacology of polyunsa turated phosphatidylcholine (PU-PC) or essential phospholipids (EPL) is followed by reports on its therapeutic effects. Further papers deal with the metabolism of the arterial wall and the presence of phospholipid related enzyme systems. Some hemody namic related effects are dealt with in the last section. These proceedings could be edited within a few months thanks to the active cooperation of the authors. The editors are grateful to acknowledge this rather unusual performance which tends to prove the interest of all participants in this sym posium. It seems logical to presume that the topic itself is an important one and that the meeting was timely organized.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
A Glossary of Essential Phospholipids, Lipids, and Lipoproteins. With 3 Figures.- Introductory Reviews.- The Biological Significance of the Plasma Phospholipids. With 13 Figures.- Lecithin-Cholesterol-Acyl-Transferase. -Lipoprotein and Phospholipid Substrate Specificity-.- Pharmacokinetics of Essential Phospholipids.- On the Pharmacokinetics of Orally Applied Essential Phospholipids (EPL). With 5 Figures.- Pharmacokinetic Studies on Phosphatidylcholine and Phosphatidylinositol. With 7 Figures.- Plasma Removal of Intravenous Essential Phospholipids in Man. With 1 Figure.- Effect of Essential Phospholipids on the ATPases and on the Fluidity of Liver Plasma Membranes. With 4 Figures.- Essential Phospholipid Therapy in Dyslipemic States.- Effects of Essential Phospholipids on the Carbohydrate-Induced Hypertriglyceridemia.- Influence of EPL on Lipolysis in Vitro and in Vivo With 7 Figures.- The Human Plasma Lipids and Lipoproteins Under Influence of EPL-Therapy. With 2 Figures.- New Analytical Approach to the Study of Hyperlipidemia. With 1 Figure.- Phospholipid Metabolism in the Arterial Wall.- Influence of Essential Phospholipids on Serum Lipids and Lipid Metabolism in the Aortic Wall. -Experiments in Normal and Atherosclerotic Rabbits- With 11 Figures.- Effect of EPL on the Metabolism of Lipids in the Arterial Wall. With 5 Figures.- Effect of EPL on the Lipid Metabolism of the Arterial Wall and Other Tissues. With 6 Figures.- Arterial Metabolism of Cholesteryl Esters -Mechanism of Action of Polyunsaturated Phosphatidylcholine- With 5 Figures.- On the Action of Essential Phospholipids in Experimental Atherosclerosis. With 4 Figures.- Essential Phospholipids in Red Cells and Thrombocytes.- Influence of Essential Phospholipids on the Flow Properties of the Blood.- The Treatment of Arterial and Venous Circulatory Disturbances with EPL. With 5 Figures.- Influence of Essential Phospholipids on Human Platelet Aggregability. With 2 Figures.
