Aging

Oxidative Stress and Dietary Antioxidants
2. Auflage 2020
ISBN: 978-0-12-818698-5
Verlag: Elsevier Science

Buch, Englisch, 398 Seiten, Format (B × H): 216 mm x 278 mm, Gewicht: 1180 g

Aging: Oxidative Stress and Dietary Antioxidants, Second Edition, bridges the trans-disciplinary divide and covers the science of oxidative stress in aging and the therapeutic use of natural antioxidants in the food matrix in a single volume. The second edition covers new trials and investigations used to determine the comprehensive properties of antioxidants, food items and extracts, as well as any adverse properties they may have. It has been updated to include new clinical human trials and a new section dedicated to animal models of aging. Throughtout the book the processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial, and oxidative stress is a single component of this.

Gerontologists, geriatricians, nutritionists, and dieticians are separated by divergent skills and professional disciplines that need to be bridged to advance preventative as well as treatment strategies. While gerontologists and geriatricians may study the underlying processes of aging, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of gerontology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of aging. This will aid in better research, treatment and outcome for patients.

Zielgruppe

Researchers of aging, gerontologists, geriatricians, nutritionists and dieticians

Autoren/Hrsg.

Preedy, Victor R.

Patel, Vinood

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Wachstum, Entwicklung, Altern
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Geriatrie, Gerontologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Ernährungsmedizin, Diätetik

Inhaltsverzeichnis

Preface

I. Oxidative stress and aging

1. Oxidative stress and mir-200c
Alessandra Magenta, Maria Cristina Florio, Marco D’Agostino, Sara Sileno

2. Caloric restriction, reactive oxygen species, and longevity
Miyuki Kobara, Hiroe Toba, Tetsuo Nakata

3. Cardiovascular disease in aging and the role of oxidative stress
Lucie Orliaguet, Vinood B. Patel, Victor R. Preedy, Fawaz Alzaid

4. Aging, oxidative stress, mitochondrial dysfunction, and the liver
Janice G. Lozada-Delgado, Carlos A. Torres-Ramos, Sylvette Ayala-Peña

5. Culprit effect of oxidative stress in the development of parkinson’s disease: a conundrum of senescence
Rahul Saxena, Gladys Rai

6. Linking bone cells, aging, and oxidative stress: osteoblasts, osteoclasts, osteocytes, and bone marrow cells
Juan A. Ardura, Luis Álvarez-Carrión, Arancha R. Gortázar, Verónica Alonso

7. Oxidative stress, senescence and mediterranean diet effects on osteoarthritis
Sergio Ammendola, Anna Scotto D’Abusco

8. Arthritis as a disease of aging and changes in antioxidant status
Rahul Saxena, Jyoti Batra

9. Oxidative stress and sarcopenia
Francesco Bellanti, Aurelio Lo Buglio, Gianluigi Vendemiale

10. Oxidative stress and hypertension in old age: the role of physical exercise
Clodoaldo Antônio De Sá, Vanessa Corralo, Francielle Garghetti Battiston, Maria Isabel Gonc¸ Alves Da Silva

11. Linking senescence, apoptosis, and oxidative stress in fertility
Mathias Abiodun Emokpae, Osaretin Godwin Igharo

12. Antioxidant capacity and menopausal symptoms
Gity Sotoudeh, Maryam Abshirini

II. Antioxidants and aging

13. Reference dietary requirements of antioxidant vitamins in the older adults
Mina Yamazaki Price, Victor R. Preedy

14. Oxidative stress and antioxidants in elderly women
Brunna Cristina Bremer Boaventura, Patricia Faria Di Pietro, Francieli Cembranel

15. Caffeine and its analogs, antioxidants, and applications
Beata Jasiewicz, Arle

Über Autor(innen)

Patel, Vinood
Vinood B. Patel, BSc, PhD, FRSC, is currently Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of liver disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress in neurological disorders and iron dysregulation in diabetes. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to the use or investigation of active agents or components. These books include The Handbook of Nutrition, Diet, and Epigenetics, Branched Chain Amino Acids in Clinical Nutrition, Cancer: Oxidative Stress and Dietary Antioxidants, Toxicology: Oxidative Stress and Dietary Antioxidants, Molecular Nutrition: Vitamins, The Neuroscience of Pain, Cognitive Behavioural Therapy. He is Editor of the ten-volume series Biomarkers in Disease: Methods, Discoveries and Applications.

Preedy, Victor R.
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.