Progress in Drug Research

Softcover Nachdruck of the original 1. Auflage 2000
ISBN: 978-3-0348-9544-6
Verlag: Springer

Buch, Englisch, Band 55, 336 Seiten, Format (B × H): 178 mm x 254 mm, Gewicht: 662 g

Reihe: Progress in Drug Research

Hepatitis C virus (HCV) was first identified in 1989 as the etiologic agent of non-A, non-B hepatitis [1] and is currently recognized as the leading cause of chronic liver disease worldwide. In contrast to hepatitis B virus infection, in which only about 5% of adult infections become chronic, more than 80% of HCV-infected patients develop chronic hepatitis. Moreover, 20-50% of those persistently infected with HCV will develop liver cirrhosis and hepatocellu­ lar carcinoma (HCC) [2]. It is estimated that there are 10,000 deaths in the USA per year due to chronic liver failure or HCC [3]. In addition, HCV dis­ 25-50% of all liver transplants in US centers, and the ease is responsible for recurrence of HCV infection following liver transplantation is universal [4]. Typically, HCV disease emerges after a 10-20 year period during which symp­ toms, if they exist at all, are mild and non-specific. Although the prevalence varies greatly among different countries, it has been estimated that up to 170 million people (3% of the world's population), are infected with HCV [5]. A recent study in the USA found that 65% of all HCV-infected persons are 30 to 49 years old [6].

Zielgruppe

Research

Autoren/Hrsg.

Weitere Mitwirkende

Wang, Q.May

Heinz, Beverly A.

Glasel, Jay A.

Reyes, Gerlie C.de los

Koda, Robert T.

Lien, Eric J.

Vedani, Angelo

Dobler, Max

Keifer, Paul A.

Mendelsohn, Laurane G.

Gupta, Satya P.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen

Inhaltsverzeichnis

Recent advances in prevention and treatment of hepatitis C virus infections.- The effects of morphine on cell proliferation.- Glucosamine and chondroitin sulfates in the treatment of osteoarthritis: a survey.- Multi-dimensional QSAR in drug research.- NMR spectroscopy in drug discovery: Tools for combinatorial chemistry, natural products, and metabolism research.- Prostate cancer and the androgen receptor: Strategies for the development of novel therapeutics.- Quantitative structure-activity relationships of cardiotonic agents.- Index Vol. 55.- Index of titles, Vol. 1-55.- Author and paper index, Vol. 1-55.