A Machine to Make a Future

Biotech Chronicles
Erscheinungsjahr 2006
ISBN: 978-0-691-12614-2
Verlag: Princeton University Press

Buch, Englisch, 224 Seiten, Format (B × H): 156 mm x 234 mm, Gewicht: 392 g

A Machine to Make a Future represents a remarkably original look at the present and possible future of biotechnology research in the wake of the mapping of the human genome. The central tenet of Celera Diagnostics--the California biotech company whose formative work during 2003 is the focus of the book--is that the emergent knowledge about the genome, with its profound implications for human health, can now be turned into a powerful diagnostic apparatus--one that will yield breakthrough diagnostic and therapeutic products (and, potentially, profit). Celera's efforts--assuming they succeed--may fundamentally reshape the fabric of how health and health care are understood, practiced, and managed.Presenting a series of interviews with all of the key players in Celera Diagnostics, Paul Rabinow and Talia Dan-Cohen open a fascinating window on the complexity of corporate scientific innovation. This marks a radical departure from other books on the biotech industry by chronicling the vicissitudes of a project during a finite time period, in the words of the actors themselves.Ultimately, the authors conclude, Celera Diagnostics is engaged in a future characterized not by geniuses and their celebrated discoveries but by a largely anonymous and widely distributed profusion of data and results--a "machine to make a future."In their new afterword, Rabinow and Dan-Cohen revisit Celera Diagnostics as its mighty machine grinds along, wondering, along with the scientists, "what constitutes success and what constitutes failure?" The pathos of the situation turns on how one poses the question as much as how one answers it.

Autoren/Hrsg.

Rabinow, Paul

Dan-Cohen, Talia

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften
• Wirtschaftswissenschaften Wirtschaftssektoren & Branchen Fertigungsindustrie Chemische Industrie
• Naturwissenschaften Biowissenschaften Humanbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik

Inhaltsverzeichnis

Overture: A MACHINE TO MAKE A FUTURE 1

Chapter One: ENDING AND BEGINNING 13

Chapter Two: THE STATE OF THINGS AT CELERA DIAGNOSTICS, EXPLAINED TO INVESTORS AND TO ANTHROPOLOGISTS 38

Chapter Three: THE MACHINERY AND ITS STEWARDS 62

Chapter Four: ETHICAL AND SOCIAL CONSULTANCY 97

Chapter Five: CONFIDENCE AND TRUST 111

Chapter Six: MODELS ORIENT, TECHNOLOGIES PERFORM, SAMPLES SPEAK (OR VICE VERSA) 144

Chapter Seven: SUMMER 2003 169

Illustrations 187

Appendix: A CORPORATE HISTORY 189

Notes 191

Glossary 195

Über Autor(innen)

Paul Rabinow is Professor of Anthropology at the University of California, Berkeley. His many books include "French DNA, Making PCR", and "Anthropos Today" (Princeton). Talia Dan-Cohen received a B.A. in anthropology from the University of California, Berkeley.