Nanotechnology Principles in Drug Targeting and Diagnosis

Erscheinungsjahr 2023
ISBN: 978-0-323-91763-6
Verlag: Elsevier Inc

Buch, Englisch, 600 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 1110 g

Nanotechnology Principles in Drug Targeting and Diagnosis focuses on the nanotechnology principles and mechanisms involved in drug targeting, nano carriers and target interactions associated with particular diseases. The book addresses how phytotherapeutics are effective against solid tumors and how they can be used in designing targeted delivery systems. Also addressed is the use of macrophages as the biomimetic carrier for targeting drugs to different organs. Sections cover the nanotechnology-based concepts in drug targeting, strategies for drug targeting, ways to identify drug carrier-target interaction, the concept of an artificial neural network in identifying drug-target interaction, and more.

The book's final section concentrates on the role of nanotechnology in medical diagnosis, throwing light on nanoscale sensors for the diagnosis of viruses in the bloodstream and biomarkers indicating various cancers. This is an important reference source for materials scientists and pharmaceutical scientists who want to understand how nanotechnology plays an important role in creating more efficient drug targeting and delivery systems.

Zielgruppe

Materials Scientists; Pharmaceutical Scientists

Autoren/Hrsg.

Rai, Mahendra

Khan, Shagufta

Belgamwar, Aarti

Fachgebiete

• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
• Technische Wissenschaften Technik Allgemein Nanotechnologie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie
• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde Materialwissenschaft: Biomaterialien, Nanomaterialien, Kohlenstoff

Inhaltsverzeichnis

SECTION 1 Drug Targeting: General Principles and Strategies 1. Drug Targeting: Nanotechnology Principles, Future Perspectives and Challenges 2. Identifying Nanocarrier-Target Interaction 3. Artificial Neural Network Based Inference of Drug - Target Interactions 4. Macrophage-Mimetic Nanomedicines for the Treatment of Diseases 5. Biopolymer Based Nanosystem for Drug Targeting 6. Pharmacokinetics of Nanomedicine

SECTION 2 Nanotechnology Approaches for Organ/Disease Specific Targeting 7. Targeted Breast Cancer Treatment: Progress and Challenges 8. Nanotechnology Advances for Improved Targeting of Solid Tumors 9. Solid Lipid Nanoparticles: The enhanced and targeted potential treatment of colorectal cancer 10. Targeted Therapy for Aggressive Lung Cancer 11. Molecular Targets for the Treatment of Angina Pectoris 12. Nanocarriers: The enhanced potential treatment of age-related macular degeneration 13. Nanotechnology Based Drug Targeting to Infectious Diseases 14. Nanotechnological strategies for drug delivery and treatment of COVID-19

SECTION 3 Nanotechnology Based Techniques for Medical Diagnosis 15. Nanotechnological tools for the diagnosis and treatment of cancer 16. Nanodiagnostics and Targeted Drug Delivery: Integrated Technologies 17. Classification of clinically actionable Genetic Mutations in cancer patients using ML based precision diagnostics 18. Nanotheranostic Applications in the Detection and Treatment of Cervical Cancer

Über Autor(innen)

Belgamwar, Aarti
Aarti Belgamwar is Assistant Professor in the in Shri Vile Parle Kelvani Mandal’s Institute of Pharmacy, Dhule. India.
Her research interests are nasal drug delivery for brain targeting, solubility enhancement, polymer modification,oral controlled drug delivery systems, and development of multi-particulate drug delivery system.

Rai, Mahendra
Mahendra Rai is an internationally recognized scholar with extensive contributions to microbial biotechnology and nanobiotechnology research, particularly in the green synthesis of metal nanoparticles using fungi and their application as nano-antimicrobials. His work is highly interdisciplinary, bridging microbiology, biotechnology, and nanoscience, and he is an active member of several scientific societies. He has received multiple national and international distinctions, including the Father T.A. Mathias Award from the All-India Association for Christian Higher Education and the Medini Award from the Government of India. Professor Rai has also held numerous visiting scientist and visiting professor positions across Europe, South America, and Asia, contributing to long-standing research collaborations in countries such as Brazil, Argentina, Hungary, Switzerland, Italy, Germany, and the United States. His sustained academic impact is reflected in his inclusion among the global top 2% of scientists in nanoscience and nanotechnology, and recognition as one of India’s leading researchers in biology and biochemistry, including a Biology and Biochemistry India Leader Award from Research.com.

Khan, Shagufta
Shagufta Khan is Professor in the Department of Pharmaceutics, Institute of Pharmaceutical Education and Research, Borgaon, India. Her areas of research are the development of drug loaded nanocarriers, nasal drug delivery for brain targeting, stability enhancement of hygroscopic and photosensitive drugs, oral controlled drug delivery systems and rapid disintegrating tablets.