Epigenetics of Exercise and Sports

Concepts, Methods, and Current Research Volume 25
Erscheinungsjahr 2021
ISBN: 978-0-12-820682-9
Verlag: Elsevier Science

Buch, Englisch, 320 Seiten, Format (B × H): 188 mm x 230 mm, Gewicht: 668 g

Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research.

Zielgruppe

<p>Human geneticists; human genomicists; translational researchers in genomic medicine, epigenetics, physiology, aging, biochemistry, sports medicine and exercise sciences, molecular biology; life science researchers; immunologists, oncologists; bioengineers; developmental biologists, physiologists</p>

Autoren/Hrsg.

Raleigh, Stuart M

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften DNA und Transgene Organismen

Inhaltsverzeichnis

Section I Concepts and methods
1. Exercise and sport: Definitions, classifications, and relevance to population health
2. Epigenetic processes—An overview
3. Methods to study exercise and sports epigenetics

Section II Current research and future perspectives
4. Nutrients, metabolism, and epigenetic change
5. Obesity epigenetics and exercise
6. Epigenetic change and different types of exercise
7. Exercise, epigenetics, and aging
8. Epigenetics, exercise, and the immune system
9. Alzheimer’s disease, epigenetics, and exercise
10. The current and future state of sports genomics
11. Epigenetic regulation and musculoskeletal injuries
12. Sports concussion and epigenetics
13. Epigenetics and doping in sports—The role of microRNAs
14. Future perspectives and concluding remarks

Über Autor(innen)

Raleigh, Stuart M
Stuart M Raleigh, BSc, FIBMS, PhD is an Associate Professor in Exercise Biochemistry and Epigenetics at Coventry University. His research interests focus on epigenetics, genetics, and biochemical mechanisms of chronic disease. He has a special interest in identifying epigenetic factors that influence the risk of musculoskeletal soft tissue pathologies and he is also exploring the link between miRNA expression and various exercise related traits. Dr. Raleigh led the University of Northampton’s Centre for Physical Activity and Chronic Disease (PACD) from 2014-2018 and he has extensive international research collaborations. His teaching interests focus on Alzheimer’s disease and multifactorial genetics. He is a Fellow of the Higher Education Academy (HEA), and Section Editor (Genetics theme) for the Journal of Sports Science and Medicine.