Translational Autoimmunity, Volume 2

Treatment of Autoimmune Diseases
Erscheinungsjahr 2022
ISBN: 978-0-12-824390-9
Verlag: Elsevier Science

Buch, Englisch, 486 Seiten, Format (B × H): 192 mm x 236 mm, Gewicht: 975 g

Translational Autoimmunity: Treatment of Autoimmune Diseases, Volume Two in the Translational Immunology series, focuses on advances in therapeutic modalities in autoimmune diseases. Efficacy and safety of not only the current biologic therapies, but also novel drug targets are discussed. Therapeutic targeting of B regulatory cells, T regulatory cells, as well as the immunomodulation effects of nanoparticles and organisms are also covered, along with our understanding and future challenges of prognostic significance of treatments in autoimmune diseases.

Autoren/Hrsg.

Rezaei, Nima

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

1. Introduction on therapeutic opportunities for autoimmunity
2. Innate lymphoid cells as therapeutic targets in autoimmune diseases
3. B regulatory cells in patients with autoimmune diseases: pathogenic significance, therapeutic potential
4. Regulatory T cells in autoimmunity and potential therapeutic targets
5. Application of IL-6 antagonists in autoimmune disorders
6. The search for monomer interaction-based alternative TNFa therapies
7. Generation of thymic cells from pluripotent stem cells for basic research and cell therapy
8. The NLRP3 inflammasome pathway in autoimmune diseases: a chronotherapeutic perspective?
9. Plasmocytes infiltrating autoimmune organs and their putative targeting
10. Biological aging and autoimmunity
11. Efficacy and safety of biologic treatment in autoimmune diseases
12. Nutritional implications for the pathophysiology and treatment of autoimmune disorders
13. Dysbiosis and probiotic applications in autoimmune diseases
14. Precision medicine in managing chronic conditions with an immunological component
15. New advanced therapy medicinal products in treatment of autoimmune diseases
16. Targeting of autoimmune disorders through metal nanoformulation in overcoming the fences of conventional treatment approaches
17. Immunomodulatory effects of parasites on autoimmunity
18. Prediction of autoimmune diseases: from bench to bedside

Über Autor(innen)

Rezaei, Nima
Nima Rezaei, MD, PhD, is Professor of Clinical Immunology and Allergy at Tehran University of Medical Sciences, where he also serves as Associate Dean of International Affairs for the School of Medicine and Director of the Global Academic Program. He is Deputy President of the Research Center for Immunodeficiencies and holds an affiliated research appointment in the Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institutet, Sweden. He earned his MD from Tehran University of Medical Sciences and his PhD in Clinical Immunology and Human Genetics from the University of Sheffield, United Kingdom. His research addresses primary immunodeficiencies and translational immunology, with recent work extending into computational and AI-based approaches to immune profiling. He is the founder and President of the Universal Scientific Education and Research Network (USERN) and serves as co-editor of the Springer Nature series Advances in Experimental Medicine and Biology.