Translational Autoimmunity, Volume 3

Autoimmune Disease Associated with Different Clinical Features
Erscheinungsjahr 2022
ISBN: 978-0-323-85415-3
Verlag: William Andrew Publishing

Buch, Englisch, 402 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 840 g

Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions.

This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases).

Autoren/Hrsg.

Rezaei, Nima

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

1. Introduction on autoimmunity and associated conditions
2. Crosstalks between autoimmunity and cancer
3. Autoinmmunity regulation within the tumor microenvironment
4. Mechanisms of immune tolerance breakdown in inborn errors of immunity
5. Autoimmunity in classic combined immunodeficiencies
6. Selective IgM deficiency and autoimmunity
7. Evans syndrome at crossroads of immune deficiency and immune dysregulation
8. Autoimmunity and HIV infection
9. M. paratubeculosis (MAP) as a zoonotic pathogen that provokes autoimmunity via molecular mimicry
10. Autoimmune diseases and metabolic disorders: molecular connections and potential therapeutic targets
11. Autoimmunity and infertility
12. Autoimmunity and its influence on human male infertility- A multi parameter approach
13. Autoimmunity and its correlation to inflammatory vascular diseases
14. Autoimmunity in atherosclerosis
15. Allergy and autoimmunity: share of genetics and environment
16. Asthma and autoimmunity
17. Autoimmunity in interstitial lung diseases
18. Role of autoimmunity in the pathogenesis of chronic obstructive pulmonary disease and pulmonary emphysema
19. Autoinflammation and cystic fibrosis
20. Autoimmunity and psychosis
21. Autoimmunity and chronic urticaria
22. Translational immunology in immune mediated oral diseases
23. Oxidative stress in oral autoimmune disorders

Über Autor(innen)

Rezaei, Nima
Nima Rezaei, MD, PhD, is Professor of Clinical Immunology and Allergy at Tehran University of Medical Sciences, where he also serves as Associate Dean of International Affairs for the School of Medicine and Director of the Global Academic Program. He is Deputy President of the Research Center for Immunodeficiencies and holds an affiliated research appointment in the Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institutet, Sweden. He earned his MD from Tehran University of Medical Sciences and his PhD in Clinical Immunology and Human Genetics from the University of Sheffield, United Kingdom. His research addresses primary immunodeficiencies and translational immunology, with recent work extending into computational and AI-based approaches to immune profiling. He is the founder and President of the Universal Scientific Education and Research Network (USERN) and serves as co-editor of the Springer Nature series Advances in Experimental Medicine and Biology.