Translational Autoimmunity, Volume 5

Challenges for Autoimmune Diseases
Erscheinungsjahr 2022
ISBN: 978-0-323-85389-7
Verlag: Elsevier Science

Buch, Englisch, 418 Seiten, Format (B × H): 191 mm x 236 mm, Gewicht: 907 g

Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing.

Zielgruppe

<p>Primary: Immunologists, Clinical immunologists; Endocrinologists; Microbiologists; Neurologists; Oncologists; Rheumatologists</p> <p>Secondary: Clinicians, research scientists, and industry partners</p>

Autoren/Hrsg.

Rezaei, Nima

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

1. Introduction on Challenges for Autoimmune Diseases 2. From horror autotoxicus to autoimmunity 3. Flow cytometry in the diagnosis of autoimmune related lymphoproliferative disorder 4. Autoantigens in atopic dermatitis: the characterization of autoantigens and their diagnostic value 5. Current paradigms and challenges in vitiligo translational research 6. The role of the kynurenine-pathway aryl hydrocarbon receptor axis in autoimmune diseases of the skin 7. COVID-19 in Childhood and Phenotypes of Pediatric Inflammatory Multisystem Syndrome 8. Challenges for epigenetics of periodontitis 9. Neutrophil extracellular traps in autoimmunity, renal diseases, and transplantation 10. Membranous nephropathy and the role of autoantibodies in its diagnosis and evolution 11. Testicular immune tolerance and viral infections 12. Ophthalmologic manifestations and management of systemic autoimmune diseases 13. Challenges for diagnosis and treatment of primary biliary cholangitis 14. Modelling autoimmune cholangiopathies as infectious disease 15. Bullous skin diseases and epitope-spreading 16. Dermatologic autoimmunity associated with immune checkpoints inhibitors 17. Insights and strategies to promote immune tolerance in allogenic hematopoietic stem cell transplantation recipients 18. The potential of cellular transplantation to harness autoimmunity and reverse clinical diabetes

Über Autor(innen)

Rezaei, Nima
Nima Rezaei, MD, PhD, is Professor of Clinical Immunology and Allergy at Tehran University of Medical Sciences, where he also serves as Associate Dean of International Affairs for the School of Medicine and Director of the Global Academic Program. He is Deputy President of the Research Center for Immunodeficiencies and holds an affiliated research appointment in the Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institutet, Sweden. He earned his MD from Tehran University of Medical Sciences and his PhD in Clinical Immunology and Human Genetics from the University of Sheffield, United Kingdom. His research addresses primary immunodeficiencies and translational immunology, with recent work extending into computational and AI-based approaches to immune profiling. He is the founder and President of the Universal Scientific Education and Research Network (USERN) and serves as co-editor of the Springer Nature series Advances in Experimental Medicine and Biology.