RNA-Binding Proteins Part B

Erscheinungsjahr 2027
ISBN: 978-0-443-47430-9
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Autoren/Hrsg.

Weitere Mitwirkende

Christianson, David

Allen, Karen N.

Chinnathambi, Subashchandrabose

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

1. Accurate prediction of RNA-binding amino acids in protein sequences with hybridRNAbind
Lukasz Kurgan
2. Direct neuronal reprogramming by transdifferentiation and application of induced neurons
Subashchandrabose Chinnathambi, Vaishnavi Anathanarayana and Tanu Suma Narayanappa
3. AGO2-Dependent Non-Canonical Interaction of miR-532-3p Mediates Regulation of Nonmuscle myosin IIC
Siddhartha S. Jana, Kumarjeet Banerjee, Shekhar Saha and Debapriya Dey
4. Method of following RNA and Protein Cargo trafficking to and out of phase-separated RNA processing bodies in mammalian cells
Suvendra Bhattacharyya and Kamalika Mukherjee
5. Comprehensive Structural Analysis of Thrombectomy Samples Using Complementary Fixation and Staining Methods
Ghulam Jeelani Pir and Aijaz Parray
6. Methods to Analyze Semi-Extractable RNAs and Their Interactions with Long non-coding RNAs and Proteins
Ashish Misra
7. Enzymatic Incorporation of a Dual-Functional Nucleotide Probe for Antibiotic-Induced Conformational Changes in the Bacterial Ribosomal RNA
Seergazhi G. Srivatsan and Saddam Khatik
8. Characterization of alpha-synuclein phase separation in cells
Samir K. Maji, Riya Bera, Ranjit Shaw and Arunima Sakunthala
9. Fluorescence Bimolecular Complementation Enables Facile Detection of Ribosome Assembly Defects in Escherichia coli
Anand Baskaran
10. A Method for Identification of RNA Targets of RNA Binding Protein by Editing
Baskar Bakthavachalu, Omkar Koppaka and Nitish Rawat
11. RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation
Loic Hamon
12. Methodologies for Deciphering TDP-43 Proteinopathy: From Genetic Modifiers to Aggregate Proteomics
Mousumi Mutsuddi, Pranjali Pandey and Ashim Mukherjee
13. RNA-protein interactions and its complexes
Indranil Malik
14. RNA-binding domains drive the double-stranded RNA recognition and binding
Jeetender Chugh
15. A proximity ligation assay (PLA)-based method for detecting the interaction of RNA-binding proteins with mRNAs in cells
Partho Sarothi Ray
16. Arginine methylation and cytoplasmic mRNA fate
Purusharth Rajyaguru, Sakshi Dewasthale and Gayatri Mohanan
17. Tah1, a key component of R2TP complex that regulates assembly of snoRNP
Deepak Kumar Sharma
18. Back Splice Junction Based Methods for Circular RNAs Detection and Enrichment
Srivatsava Naidu and Deepika Antil
19. Suppressor mutation screening to understand the molecular mechanisms of RNA-protein interaction in translation
Pankaj V. Alone, Charles Antony and Tanaya Kole
20. RNA based therapeutics in Inflammation Model NSCLC
Shailza Singh, Pooja Gulhane, Manasi Tukrul and Swati Goswami
21. Non-coding RNA-RBP complexes in Epigenetic Regulation during Megakaryocyte Development
Ravi Kumar Gutti
22. Methods of regulated and cooperative miRNA packaging into the endosomal lumen by miRNA-binding protein HuR
Suvendra Bhattacharyya and Kamalika Mukherjee
23. Biophysical characterization of p53 tetramerization domain mutant R337C
Abdul Samath Ethayathulla

Über Autor(innen)

Chinnathambi, Subashchandrabose
Subashchandrabose Chinnathambi is Additional Professor at the Department of Neurochemistry, National Institute of Mental Health and Neurosciences Hospital Bangalore, Karnataka, India. His scientific interests include physiopathology of neurodegenerative disorders, Tau Cytoskeleton, Tau-GPCR, purinergic and chemokine receptors, Tau stem cells, animal models, neuropharmacology, therapeutic approaches targeting Tau oligomers, and biomarkers for neurodegeneration. He serves on the editorial board for various international cell biology journals and is also a regular invited speaker at a number of meetings and workshops. Dr. Chinnathambi has more than 16 years of research experience in the area of neuroscience and Tau-related research in Alzheimer’s Disease.

Allen, Karen N.
Dr. Karen N. Allen works at the Department of Chemistry of the Boston University, the Metcalf Center for Science and Engineering

Christianson, David
After completing studies for the A.B., A.M., and Ph.D. degrees in chemistry at Harvard University, David W. Christianson joined the faculty of the University of Pennsylvania, where he is currently the Roy and Diana Vagelos Professor in Chemistry and Chemical Biology. At Penn, Christianson’s research focuses on the structural and chemical biology of the zinc-dependent histone deacetylases as well as enzymes of terpene biosynthesis. His research accomplishments have been recognized by several awards, including the Pfizer Award in Enzyme Chemistry and the Repligen Award in Chemistry of Biological Processes from the American Chemical Society, a Guggenheim Fellowship, and the Elizabeth S. and Richard M. Cashin Fellowship from the Radcliffe Institute for Advanced Study at Harvard University. Christianson is also a dedicated classroom teacher, and his accomplishments in this regard have been recognized by the Lindback Award for Distinguished Teaching at Penn and a Rhodes Trust Inspirational Educator Award from Oxford University. Christianson has also held visiting professorships in the Department of Biochemistry at Cambridge University and the Department of Chemistry and Chemical Biology at Harvard University. Christianson has served with Prof. Anna Pyle as Co-Editor-in-Chief of Methods in Enzymology since 2015.