Buch, Englisch, Band 221, 295 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 4628 g
Buch, Englisch, Band 221, 295 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 4628 g
Reihe: Handbook of Experimental Pharmacology
ISBN: 978-3-662-51202-9
Verlag: Springer
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Overview: biophysical properties and structure of sodium channels.- The voltage sensor module in sodium channels.- Slow inactivation of Na+ channels.- Regulation/modulation of sensory neuron sodium channels.- Ubiquitylation of voltage-gated sodium channels.- Probing gating mechanisms of sodium channel using pore blockers.- Animal toxins influence voltage-gated sodium channel function.- Voltage-sensor trapping toxins: Iso form-specific ligands for sodium channels.- Pharmacological insights and quirks of bacterial sodium channels.- The role of non-pore-forming ß subunits in physiology and pathophysiology of voltage-gated sodium channels.- The role of late INa in development of cardiac arrhythmias.- Proton modulation of cardiac INa: A potential arrhythmogenic trigger.- Altered sodium channel gating as molecular basis for pain: Contribution of activation, inactivation and resurgent currents.