Buch, Englisch, 106 Seiten, Previously published in hardcover, Format (B × H): 165 mm x 248 mm, Gewicht: 219 g
Buch, Englisch, 106 Seiten, Previously published in hardcover, Format (B × H): 165 mm x 248 mm, Gewicht: 219 g
Reihe: Molecular Biology Intelligence Unit
ISBN: 978-1-4419-2693-7
Verlag: Springer
his book is devoted to vascular endothelial growth factor A (VEGF his book is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for or VEGFA), a secreted signalling protein of great significance for T development and disease in vertebrates. VEGFAcontrols the prolif Tdevelopment and disease in vertebrates. VEGFA controls the prol- eration, eration, migration migration, specialisatio specialisation n and and surviva survival l of vascula ofvascular r endothelia endothelial l cells, cells, and and iit t isis therefor therefore e essentia essential l for th for e establishmen the establishment t of a functiona ofa functional l blood vesse blood l vessel circuit. circuit. IIn n addition addition, VEGF VEGFA A is emergin is emerging g as a versatil as a versatile e patternin patterning g factor fofactor r for several several non endothelia non-endothelial l celcell l type types s in vertebrates in vertebrates. ThusThus, it playit s a centra plays al rol central e role during organ development at multiple levels, including blood vessel growth, duringorgan developmentat multiple levels, including blood vessel growth, vessel-mediated vessel mediated orga organ n inductio induction n andand tissutissue e differentiation differentiation. The The discover discovery y ofof non endothelia non-endothelial l rolesroles for VEGF for VEGFA A initiallinitially y came ascarne a as a surprise. surprise.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
- Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie
Weitere Infos & Material
The Biology of Vascular Endothelial Cell Growth Factor Isoforms.- VEGF Receptor Signalling in Vertebrate Development.- VEGF Gene Regulation.- Embryonic Vasculogenesis and Hematopoietic Specification.- Role of VEGF in Organogenesis.- VEGF and Endothelial Guidance in Angiogenic Sprouting.- Vascular and Nonvascular Roles of VEGF in Bone Development.- VEGF in the Nervous System.
