Transfusion Medicine and Hemostasis

Clinical and Laboratory Aspects
4. Auflage 2024
ISBN: 978-0-323-96014-4
Verlag: Elsevier LTD

Buch, Englisch, 890 Seiten, Format (B × H): 216 mm x 277 mm, Gewicht: 2430 g

**Selected for 2025 Doody’s Core Titles® in Laboratory Medicine**

Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects, Fourth Edition continues to be the only "pocket-size" quick reference for pathology and transfusion medicine for residents and fellows. It is helpful to all physicians and allied health professionals who order and administer blood components, cellular therapies, specialized factors for hemostatic abnormalities, coagulation testing, and those who consult and care for these often very ill patients. This book is ideal for pathology, medicine, surgery, and anesthesia residents, transfusion, hematology, and anesthesia fellows, and certified and specialized practitioners, as well as medical technologist in transfusion, cellular therapy, hematology, and coagulation. This new edition covers the many new developments that have occurred since the previous edition to include new blood products, new indications, or clinical conditions in which blood products are used. Similarly, new hemostasis testing is introduced as well as new clinical scenarios due the COVID-19 pandemic that area relevant to hemostasis and transfusion medicine. This includes COVID coagulopathy, Vaccine Induced Thrombotic Immune Thrombocytopenia, Pediatric reference range in coagulation testing, Platelet rich plasma and MNC products – CAR-T cells.

Autoren/Hrsg.

Shaz, Beth H.

Gil, Morayma Reyes

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Anästhesiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Hämatologie, Transfusionsmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie

Inhaltsverzeichnis

1. Blood banking and transfusion medicine – the field, the discipline and the industry

2. Quality principles in Transfusion medicine

3. Regulatory issues in transfusion medicine

4. Role of the physician in the blood center

5. Blood donor, donation process and technical aspects of blood collection

6. Apheresis blood component collections

7. Recipient-specific blood donations

8. Adverse donor reactions (iron)

9. Component preparation and manufacturing

10. Serologic testing of donor products

11. Overview of infectious disease testing

12. HIV screening

13. Hepatitis B screening

14. Hepatitis C screening

15. WNV screening

16. Zika screening

17. Babesia screening

18. Syphilis, HTLV and Chagas screening

19. Bacterial mitigation of platelets

20. Role of the transfusion service physician

21. Pretransfusion testing

22. Antibody identification

23. Direct antiglobulin test

24. Molecular DNA based blood group typing

25. ABO and H blood group systems

26. RH and RhAg blood group system

27. KELL and KIDD blood group systems

28. MNS AND DUFFY blood group systems

29. LEWIS, I P1Pk and Glob blood group systems

30. Other blood group systems, collections, and antigens

31. Human platelet and neutrophil antigens

32. HLA Antigens

33. Red blood cells products

34. Plasma products

35. Platelet products (to include PAS if not previously mentioned; was mentioned In the 2nd edition)

36. Cryoprecipitate and fibrinogen concentrates

37. Granulocyte products

38. Albumin and related products

39. Human immunoglobuin preparations

40. Rh immune globulin

41. Coagulation Factor products

42. Platelet rich plasma

43. Convalescent plasma, including COVID convalescent plasma

42. Nonfactor therapies for bleeding disorders

44. Blood Pharming and alternative blood production methods

45. Irradiation of blood products

44. Leukoreduction of blood products

46. CMV-safe blood products

47. Frozen blood products

48. Washed blood products

49. Volume reduced blood products

50. Pathogen reduction technologies

51. Intrauterine, Neonatal and pediatric transfusion medicine

52. Perinatal transfusion medicine

53. AutoImmune hemolytic anemias

54. Transfusion management in patients with hemoglobinopathies

55. Transfusion of Patients Undergoing Hematopoietic Stem Cell Transplantation

56. Transfusion of Patients Undergoing Solid Organ Transplantation

57. Transfusion support and hemostatic monitoring in patients connected to extracorporeal devices

58. Transfusion of patients receiving antithrombotic therapy

59. Blood transfusion in economically restricted and developing countries

60. Management of Patients Who Refuse Blood Transfusion

61. Platelet transfusion refractory patients

62. Massive transfusion

63. Patient blood management

64. Overview of adverse events and outcomes following transfusion

65. Febrile non-hemolytic transfusion reactions

66. Allergic transfusion reactions

67. Acute hemolytic transfusion reactions

68. Delayed hemolytic transfusion reactions

69. Transfusion-Associated Circulatory Overload

70. Transfusion-Related Acute Lung Injury

71. Septic transfusion reactions

72. Metabolic, hypotensive and other acute reactions and complications

73. Post transfusion purpura

74. Transfusion associated graft versus host disease

75. Transfusion related immunomodulation

76. Iron Overload

77. Transfusion transmitted diseases

78. Overview to therapeutic apheresis
79. Therapeutic plasma exchange

80. Therapeutic erythrocytapheresis

81. Therapeutic thrombocytapheresis

82. Therapeutic leukocytapheresis and adsorptive cytapheresis

83. Extracorporeal photopheresis

84. LDL apheresis

85. Immunoabsorption

86. COVID-19 & Apheresis

87. Therapeutic phlebotomy

88. Overview of cellular therapy

89. HPC products derived from bone marrow and peripheral blood

90. Cord blood banking (expansion)

91. Regenerative medicine (iPS)

92. Immunotherpy (T cells): CAR-T, TILs, gene therapy and more

93. Adverse events associated with

Über Autor(innen)

Gil, Morayma Reyes
Morayma Reyes Gil, MD, PhD, is an associate professor in the Department of Pathology at Montefiore Medical Center (MMC) and Albert Einstein College of Medicine. As the director of hematology and special coagulation laboratories, Dr. Reyes Gil oversees all hematology and coagulation laboratories at all MMC hospitals, collaborates in clinical research and clinical trial studies and continues translational research in vascular biology. She started her career in academic pathology at the University of Washington as an assistant professor in the Department of Pathology and laboratory Medicine. Dr. Reyes Gil has been a recipient of several awards and research grants from private research foundations and from the National Institutes of Health. Dr. Reyes Gil is board certified in clinical pathology and has authored over 50 peer-reviewed articles in the field of vascular biology. Dr. Gil is a graduate of the University of Puerto Rico. She received her MD and PhD from the University of Minnesota. She then completed a residency in clinical pathology and specialized in coagulation and benign hematology at the University of Washington.

Shaz, Beth H.
Beth H. Shaz, MD, is Chief Medical and Scientific Officer, Executive Vice President at New York Blood Center, and Adjunct Assistant Professor, Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University. Beth is responsible for all medical and scientific activities throughout the NYBC network, which includes Rhode Island Blood Center, Innovative Blood Resources (Memorial Blood Center and Nebraska Blood Center), Community Blood Center of Greater Kansas City, and Blood Bank of Delmarva. Medical activities comprise of hemophilia services, clinical apheresis services, perioperative autologous transfusion services, cellular therapy, medical education, medical consultation, transfusion services, bone marrow donor recruitment, and donor management. Scientific activities include basic science at the Lindsey F. Kimball Research Institute and Comprehensive Cell Solutions (CCS), which contains translational and clinical research. NYBC’s scientific and medical activities focus on transfusion medicine, cell therapy, regenerative medicine, infectious disease, hematology, and personalized medicine. Beth is an editor of ten books in transfusion medicine, author of over 130 articles pertaining to transfusion medicine. She is an associate editor of TRANSFUSION and on the editorial board of BLOOD. Previously, she was an Associate Professor at Emory University School of Medicine and director of the transfusion service at Grady Memorial Hospital. Also, she was an instructor at Harvard Medical School and associate director of the transfusion service at Beth Israel Deaconess Medical Center in Boston. Beth received her MD with research distinction from the University of Michigan and BS in chemical engineering with distinction from Cornell University. She completed a general surgery internship at Georgetown University, an anatomic & clinical pathology residency at Beth Israel Deaconess Medical Center, and a transfusion medicine fellowship at Harvard Medical School.