Sheikh / Platts-Mills / Worth | Landmark Papers in Allergy | Buch | 978-0-19-965155-9 | www.sack.de

Buch, Englisch, 360 Seiten, Format (B × H): 175 mm x 250 mm, Gewicht: 800 g

Sheikh / Platts-Mills / Worth

Landmark Papers in Allergy


Erscheinungsjahr 2012
ISBN: 978-0-19-965155-9
Verlag: ACADEMIC

Buch, Englisch, 360 Seiten, Format (B × H): 175 mm x 250 mm, Gewicht: 800 g

ISBN: 978-0-19-965155-9
Verlag: ACADEMIC


The increasing incidence and prevalence of allergic disease worldwide is one of the most remarkable phenomena of the past 50 years. One in three people in developed countries will experience an allergic condition at some point in their lives and advances in understanding the causes of this trend, and in allergy treatment and care, have captured the imagination of scientists, clinicians and the public.

Landmark Papers in Allergy is a definitive collection of over 90 papers charting key discoveries and scientific advances in relation to allergy and the development of treatment and care for allergic disorders. Comprehensive in its coverage, the book includes the first clear descriptions of allergic diseases; the major advances in treatments, such as the discovery of antihistamines, cortisone, biological therapies and immunotherapy; the great immunological advances, such as the discovery of immunoglobulin E (IgE) and leukotrienes; the possible factors behind the increase in allergy, such as the house dust mite, changes in hygiene and diet; and the growing understanding of the social, psychological and quality-of-life consequences of allergy.

Including authoritative commentaries from leading international experts providing reflections on the historical importance and current relevance of each landmark paper, Landmark papers in Allergy is essential reading for any clinician or academic with an interest in allergy.

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Weitere Infos & Material


- SECTION I: 1800-1899

- 1: Jean Bousquet and Pascal Demoly: Did Bostock Discover Allergic Rhinitis?

- 2: Gailen D. Marshall, Jr.: Early Insights into the Characteristics of Asthma

- 3: Gailen D. Marshall, Jr.: Identifying Asthma Triggers

- 4: Aziz Sheikh: Innovative Experiments Which Helped to Unravel the Aetiological Basis of Hay Fever

- 5: Brian Hurwitz: Asthma Enters the Medical Mainstream

- SECTION II: 1900-1949

- 6: Barry Kay: What's in a Name? First Use of the Term 'Allergy'

- 7: Gideon Lack: An Innovative Treatment for Food Allergy

- 8: Glennis Scadding: Laying the Foundation for Specific Immunotherapy

- 9: Torsten Zuberbier: Celebrating the Case Study: Schloss' Description of Atopic Dermatitis

- 10: Phil Lieberman: Richet's Nobel Lecture

- 11: Madeleine Ennis: A Serendipitous Discovery

- 12: Anthony J Frew and Helen E Smith: Cooke's Early Insights into the Potentially Curative Role of Immunotherapy for Hay Fever

- 13: Michael Ardern-Jones:. Does Eczema Have an Allergic Aetiology?

- 14: Michael Ardern-Jones:.and What about Angioedema and Urticaria?

- 15: Jonathan Brostoff and A. William Frankland: Prausnitz, Küstner and the First Diagnostic Test for Allergy

- 16: Harold S. Nelson: Introducing Atopy

- 17: Munir Pirmohammed: Ephedra - Laying the Foundations for Modern Autonomic Pharmacology

- 18: Hasan Arshad: First Attempts to Unravel the Relationship between Diet and Allergy

- 19: N. Franklin Adkinson Jr: Demonstrating Serological Changes Induced by Ragweed Extract

- 20: Martin K Church and Marcus Maurer: Bovet's Nobel Prize-winning Discovery of Antihistamines

- 21: Sven-Erik Dahlén: Identification of Slow-Reacting Substance

- 22: Victoria Cardona and Ignacio J. Ansotegui: Oral Allergy Syndrome

- SECTION III: 1950-1999

- 23: Andrew Bush: In Praise of Famous Men: Early Cortisone Studies

- 24: Michael Kaliner: The Relationship between Mast Cells and Histamine

- 25: Stephen R Durham: What Goes Round Comes Around: Developing Allergen Immunotherapy

- 26: Sarah Howie: Burnet, Clonal Selection Theory and Acquired Immunological Tolerance

- 27: Marc Peters-Golden: Slow-Reacting Substance of Anaphylaxis

- 28: Anthony Dubois: Loveless and Wasp-venom Immunotherapy

- 29: Stephen Wasserman: Developing an Understanding of Mast Cell Biology

- 30: Alan Edwards: Disodium Cromoglycate for Allergic Asthma

- 31: Anant Parekh: Ancient Egyptian Soup for Treating Asthma: Cox and Intal

- 32: Shuaib Nasser: RAST: The Iconic Test for Allergic Sensitisation

- 33: Sami L Bahna: The Discovery of IgE

- 34: Lanny Rosenwasser: Penicillin Allergy: A Model for Practical Clinical Translational Science

- 35: Angela Simpson: Unravelling the Relationship between Dermatophagoides Pteronyssinus and Asthma

- 36: William W. Busse: The Gell and Coombs Classification

- 37: Hannah Gould: The Dawn of Molecular Allergology

- 38: Walter Canonica: Immunotherapy Can Change the Natural History of Respiratory Allergy

- 39: Paul O'Byrne: Anatomy of the Asthmatic Bronchi

- 40: Paul Cullinan and Anthony Newman Taylor: Identifying a Novel Cause of Occupational Allergy

- 41: Tom Platts-Mills: Delayed Hypersensitivity to Pollen Allergens

- 42: Aziz Sheikh: Inhaled Beclomethasone Dipropionate: Stepping-up Asthma Care

- 43: Thomas Ruzicka and Andreas Wollenberg: Challenging Notions of the "Atopic Personality"

- 44: Graham Roberts: Establishing and Investigating the Relationship between Food Allergy and Asthma

- 45:. Bruce R Thompson and Robyn E O'Hehir: The "Histamine-Inhalational Test"

- 46: Jasmeet Soar: Allergic Reactions to Colloid Infusions-Another Chapter in the Colloid Debate

- 47: Paul Greenberger: Total and Specific IgE and Allergic Bronchopulmonary Aspergillosis

- 48: Richard F. Lockey: Immunotherapy for Venom Allergy Comes of Age

- 49: Roy Gerth van Wijk: Extending the Evidence for Immunotherapy to the Management of Children with House Dust Mite Triggered Asthma

- 50: Peter Burney: Insights from Xhosa into Environmental Risk Factors for the Development of Asthma

- 51: Jürgen Schwarze: Viral Infection, Allergic Sensitisation and Asthma

- 52: Johannes Ring and Ulf Darsow: Immune Responses in Atopic Eczema

- 53: Todor Popov:. Understanding the Relationship between Atopic Sensitisation and Airway Hyper-responsiveness in Asthma

- 54: Alessandro Fiocchi: Key Insights into the Relationship between Food Allergy and Atopic Dermatitis

- 55: Frank Austen: From Slow-Reacting Substance of Anaphylaxis to Anti-Leukotrienes

- 56: Karl Staples and Ratko Djukanovic: Once More unto the Breach: the Role of the Damaged Bronchial Epithelium in Asthma

- 57: Simon Brown: Management of Anaphylactic Shock

- 58: Graham Devereux: The Hygiene Hypothesis

- 59: Diane Gold: In Search of the Elixir for Childhood Allergy and Asthma

- 60: Allison Worth: A New Way of Considering 'Quality of Life'

- 61: Scott Sicherer: Food Allergy and Anaphylaxis

- 62: Sandra Kuiper and Constant P. van Schayck: Allergen Avoidance: The Isle of Wight Study

- 63: Parameswaran Nair: Introducing Sputum Counts

- 64: David Ahern: Atopic Asthma is a TH2-cell Mediated Disease

- 65: Samantha M Walker: Investigating the Impact of Hay Fever on Educational Performance

- 66: Tomohiro Utsunomiya and Motohiro Ebisawa: Findings from an Early Peanut Immunotherapy Trial

- 67: Young Min Ye and Hae-Sim Park: Auto-Immune Mechanisms in Chronic Urticaria

- 68: Frank J Kelly: Air Pollution, Mortality and the Need for Public Health Policy

- 69: Seif Shaheen: The Geography of Asthma and Atopy: After the Berlin Wall Came Down

- 70: Judith Woodfolk: The Role of Animal Allergens in Allergic Disease

- 71: Innes Asher and Julian R Vyas: The Natural History of Wheezing: the Tucson Cohort

- 72: Stacy Chin and Wesley Burks: Measuring Food-Specific IgE Values

- 73: Mary Linehan: Tuberculosis Exposure and Atopy

- 74: James Friedlander and Wanda Phipatanakul: The Inner-City Home Environment and Asthma

- 75: Carsten Flohr: Mapping the Burden of Allergic Disease in Childhood: ISAAC

- 76: David Beuther: The Relationship between Obesity and Asthma

- 77: Michael Daines and Wayne Morgan: The Emergence of Monoclonal Antibodies

- 78: John Warner: The Renaissance in Allergen Immunotherapy

- 79: Somnath Mukhopadhyay: Pet Exposure in Early Life and the Development of Allergy and Asthma

- SECTION IV: 2000-2012

- 80: Denis Ownby: Predicting the Development of Childhood Asthma

- 81: Andrew J Wardlaw: IL-5 Blocking Monoclonal Antibody

- 82: Simon Brown: Learning from Anaphylaxis Fatalities

- 83: Audrey DunnGalvin: Peanut Allergy and Quality of Life

- 84: Erika von Mutius: The Janus Face of Endotoxin: for Good and Bad?

- 85: Carlos Camargo: Testing the 'Hygiene Hypothesis': Probiotics for the Primary Prevention of Atopic Eczema

- 86: Antonella Muraro: The Impact of Food Allergy on Health-Related Quality of Life

- 87: Stephan Bischoff: Does Idiopathic Eosinophilic Esophagitis have an Allergic Aetiology?

- 88: Ian M Adcock: Dawn of the Genomic Age for Asthma

- 89: Malcolm Sears: Endotoxins, Allergy and Tolerance

- 90: William Cookson: Inherited Skin-Barrier Defects and Risk of Developing 'Atopic' Eczema

- 91: Ulrich Wahn: Anti-IgE: Biologicals Reach the Inner-cities

- 92: Tom Platts-Mills, Allison Worth and Aziz Sheikh: Conclusions: From the 18th to the 21st Century, and Beyond.


Aziz Sheikh trained in Physiology and Medicine, graduating from UCL, Londonn in 1990 and 1993. After completing his training in general practice, he decided to specialise in the field of epidemiology. He has held academic posts in the Departments of Primary Health Care & General Practice at Imperial College, London and Public Health Sciences at St George's Hospital Medical School, London. He has since August 2003 held the post of Chair in Primary Care Research & Development in the Centre for Population Health Sciences at The University of Edinburgh. He is an Honorary Consultant in Paediatric Allergy in NHS Lothian. His major research interest is in studying the epidemiology and primary care management of asthma and allergic disorders, and he has published extensively in this area.

Tom Platts-Mills is Professor of Medicine and Microbiology in the School of Medicine at the University of Virginia. He is a graduate of Balliol College, Oxford, and St. Thomas Hospital Medical School. He carried out a fellowship in allergy and immunology at Johns Hopkins University, working in the laboratory of Dr. Kimishige Ishizaka. From 1974-1982, he worked for the Medical Research Council at Northwick Park and completed his PhD in 1982 at London University. Since 1982, he has been head of the Division of Asthma, Allergy, and Immunology at the University of Virginia. He served as president of the American Academy of Allergy, Asthma, and Immunology (AAAAI) from 2006 to 2007. He has researched the immune response to a range of allergens, including those from pollens, dust mites, the fungus Trichophyton, and domestic cats. In 2010, Dr. Platts-Mills was elected as a Fellow of the Royal Society.

Allison Worth trained as a nurse and worked in hospital and community settings and as a lecturer in nursing before undertaking a PhD and specialising in qualitative research. She currently manages the Allergy and Respiratory Research Group at The University of Edinburgh. Her research interests are in patient, family and health professional experiences of long-term illness and healthcare.



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