Biotechnology Engineering

Erscheinungsjahr 2025
ISBN: 978-0-443-31476-6
Verlag: Elsevier Inc

Buch, Englisch, 476 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 812 g

Biotechnology Engineering: A Practical Approach on Bioprocess Development from Lab to Industrial Scale offers a comprehensive guide on biotechnology engineering, focusing on transforming research and development into commercially viable industrial processes. The book addresses the needs of the market by providing structured chapters, practical methods, and real-world case studies. Readers will gain valuable insights into bioprocessing basics, scalable solutions, optimization techniques, and collaboration opportunities. The text also covers essential regulatory compliance information, bridging the gap between theoretical knowledge and practical applications.

The book is a vital resource for academics, scientists, engineers, and professionals in bioprocess development. It includes detailed discussions, calculations, and case studies, modern bioreactors, and software tools used in the industry. Serving as a desktop reference, it effectively combines theory with real-world applications to support the development of bioprocesses on all scales.

Autoren/Hrsg.

Shet, Vinayaka B.

Kanthakere, Sandesh

Mubarak, Nabisab Mujawar

Karri, Rama Rao

Hadi Dehghani, Mohammad

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie

Inhaltsverzeichnis

PART A: Cell culture and Kinetic study
1. Culturing of microbial, animal and plant cells in lab scale
2. Microbial growth and cell kinetics
3. Design, optimization, and Inoculum development for culturing the cells
4. Lab scale studies on Submerged Liquid Fermentation (SLF) and Solid State Fermentation (SSF)

PART B: Bioreactor handling and operation
5. Fundamental of Bioreactors and accessories
6. Design Aspects and Aseptic Maintenance of Bioreactors

7. Cleaning Techniques for Bioreactors and Regulatory Standards
8. Bioreactor sterilization techniques and equipment
9. Standard Operating Procedures and Auditing in Bioprocess Industries
10. Operation and control of Submerged Liquid Fermenters
11. Operation and control of submerged solid fermenters
12. Equipment for downstream Product Recovery and Purification
13. Modern Reactors and Software Tools in Bioprocess Development

PART C: Bioreactor Scale up aspects and case studies
14. Scale-Up Rules and Reactor Accessories
15. Scale-Up Strategies for Submerged Liquid Fermentation

16. Scale-Up Strategies for Solid State Fermentation
17. Scale-Up Constraints from Lab Scale to Industrial Scale

PART D: Bioproducts
18. Commercial Bioproducts from Bioreactors
19. Bioproducts from Fermentation and their Economic Impact
20. Manufacturing Techniques for Bioproducts

Über Autor(innen)

Hadi Dehghani, Mohammad
Professor Mohammad Hadi Dehghani is a faculty member in the Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences (TUMS), Iran. His research focuses on environmental science, and he leads research projects at TUMS. He contributes to scholarly journals as an editorial board member, guest editor, and reviewer and participates in international scientific committees. He also supervises postgraduate research and is a member of the Iranian Association of Environmental Health and the Institute for Environmental Research at TUMS. His scholarly work includes peer-reviewed research, conference papers, book chapters, and edited volumes.

Shet, Vinayaka B.
Dr. Vinayaka B Shet is an Associate Professor in the Department of Biotechnology Engineering, NMAMIT, off-campus centre, Nitte (Deemed to be university), Nitte, Karnataka, India. He holds a Ph.D. in Biotechnology from VTU Belgavi, an M.Tech. in Industrial Biotechnology from the National Institute of Technology Karnataka (NITK), and a B.E. in Biotechnology from P.A. College of Engineering, Mangaluru. He has over 18 years of experience in Academics, 10 years in Research, and 1 year in Industry. He received a young researcher award. He has published over 30 research articles and 10 book chapters and holds two Indian patents. He is a reviewer of various journals. He serves as Coordinator (Accreditation and Compliance) at Nitte (Deemed to be University), Mangaluru, India.

Kanthakere, Sandesh
Dr. Sandesh K is an Assistant Professor in the Department of Biotechnology Engineering, NMAMIT, off-campus centre, Nitte (Deemed to be university), Nitte, Karnataka, India. He holds a Ph.D. in Biotechnology from VTU Belgavi, and M.Tech. in Chemical Plant Design from the National Institute of Technology Karnataka (NITK), and B.E. in Chemical from B.M.S. College of Engineering, Bengaluru. He has over 14 years of experience in Academics and Research. He has many international and national publications in reputed journals and book chapters. He holds few Indian patents in his area of research. He is a reviewer of various journals.

Karri, Rama Rao
Rama Rao Karri is an Associate Professor in the Faculty of Engineering at Universiti Teknologi Brunei. He holds a PhD from IIT Delhi and a Master’s from IIT Kanpur in Chemical Engineering. With over 20 years of experience in academia, industry, and research, he has experience working in multidisciplinary fields and has expertise in various evolutionary optimization techniques and process modelling. His expertise extends to process modeling and simulation, focusing on optimizing chemical and environmental processes to improve efficiency and sustainability. He serves on editorial boards of several international journals and acts as a peer reviewer for numerous reputed publications. He is also a guest editor for special issues on nanocomposites and environmental engineering topics. Additionally, he contributes to authoring and editing books on sustainable technologies, environmental remediation, and process monitoring with leading academic publishers.

Mubarak, Nabisab Mujawar
Dr. Nabisab Mujawar Mubarak is an Associate Professor in the Department
of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia.He is a scientific reviewer for numerous Chemical Engineering
andNanotechnology journals. In research, Dr.Mubarak has published
over 450 journal papers and 40 conference proceedings, authored 85
book chapters, and has an H-index of 87. His areas of interest include
the synthesis of carbon nanomaterials, the production of magnetic
biochar using microwaves, and wastewater treatment utilizing advanced
materials. He received the Curtin Malaysia Most Productive Research Award, the Outstanding Faculty of Chemical Engineering Award, the Best Scientific Research Award in London, and the Exceptional ScientistAward in publication and citation by
i-Proclaim, Malaysia. Since 2020, he has also been listed among the top 2% of the world’s most influential scientists in the fields of chemistry and energy. The List of the Top 2% of Scientists in
the World, compiled and published by Stanford University, is based on international scientific
publications, the number of scientific citations for research, and participation in the review and
editing of scientific research. Dr. Mubarak is a Fellow Member of the Institution of Engineers
Australia, a Chartered Professional Engineer of The Institution of Engineers Australia, and a
Chartered Chemical Engineer of the Institute of Chemical Engineering, UK. He has published
11 books and is coeditor for ongoing Elsevier-edited books: 1) Nanomaterials for Carbon
Capture and Conversion Technique, 2) Advanced Nanomaterials and Nanocomposites for Bioelectrochemical Systems, 3) Water Treatment Using Engineered Carbon Nanotubes,4)
Hybrid Nanomaterials for Sustainable Applications: Case Studies and Applications, 5), Sustainable
Nanotechnology for Environmental Remediation, 6) Nanotechnology for Biomedical
Applications,7) Nanotechnology for Electronic Applications, 8) Application of Bio-Additives
for the Food Industry, 9) Contemporary Nanomaterials inMaterial Engineering Applications,
10)Fundamentals of Biomaterials: ASupplementary Textbook, 11) EmergingWater Pollutants:

Concerns and Remediation Technologies.