Buch, Englisch, Band 1, 184 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 465 g
Reihe: Translational Bioinformatics
Buch, Englisch, Band 1, 184 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 465 g
Reihe: Translational Bioinformatics
ISBN: 978-94-007-5557-4
Verlag: Springer Netherlands
"Applied Computational Genomics" focuses on an in-depth review of statistical development and application in the area of human genomics including candidate gene mapping, linkage analysis, population-based, genome-wide association, exon sequencing and whole genome sequencing analysis. The authors are extremely experienced in the area of statistical genomics and will give a detailed introduction of the evolution in the field and critical evaluations of the advantages and disadvantages of the statistical models proposed. They will also share their views on a future shift toward translational biology. The book will be of value to human geneticists, medical doctors, health educators, policy makers, and graduate students majoring in biology, biostatistics, and bioinformatics. Dr. Yin Yao Shugart is investigator in the Intramural Research Program at the National Institute of Mental Health, Bethesda, Maryland USA.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
- Mathematik | Informatik EDV | Informatik Angewandte Informatik Bioinformatik
- Naturwissenschaften Biowissenschaften Angewandte Biologie Bioinformatik
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizinische Mathematik & Informatik
- Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
- Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
Weitere Infos & Material
Introduction.- Concepts of Genetic Epidemiology.- Integration of Linkage Analysis and Next Generation Sequencing Data.- From Family Study to Population Study: A history of Genetic Mapping for Nasopharyngeal Carcinoma (NPC).- QTL Mapping of Molecular Traits for Studies of Human Complex Diseases.- Renewed Interest in Haplotype: from Genetic Marker to Gene Prediction.- Analytical Approaches for Exome Sequence Data.- Rare Variants Analysis in Unrelated Individuals.- Gene Duplication and Functional Consequences.- From GWAS to Next-Generation Sequencing on Human Complex Diseases: the Implications for Translational Medicine and Therapeutics.
