Immunotherapy for Autoimmune Disorders

Innovations and Insights
Erscheinungsjahr 2026
ISBN: 978-0-443-33236-4
Verlag: Elsevier Science

Buch, Englisch, 200 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 449 g

Immunotherapy for Autoimmune Disorders: Innovations and Insights revolutionizes the therapeutic paradigm for autoimmune illnesses, offering new perspectives over traditional medication therapies. This complete and accessible resource examines how immunotherapy teaches the immune system to detect and fight targeted cells, enhancing the body's immune response by providing additional components to strengthen its defense mechanisms. The book covers a wide range of topics, including the pathophysiology, diagnosis, and classification of autoimmune diseases, the immunopathogenesis of these disorders, and the development and application of monoclonal antibodies. It explores immune checkpoint inhibitors, T-cell modulation therapies, cytokine targeting therapies, B-cell depletion strategies, and more.

Additionally, it addresses immunomodulatory agents, small molecules, personalized immunotherapy approaches, and the application of immunotherapeutic strategies for specific autoimmune diseases. Future directions and emerging therapies, as well as regulatory and ethical considerations, are also discussed. This is essential reading for medical professionals, researchers, and students seeking to learn about immunotherapy as an alternative approach to treating autoimmune disorders.

Autoren/Hrsg.

Singh, Arun Kumar

Bandaru, Nagaraju

Apostolopoulos, Vasso

Pareek, Ashutosh

Yallapu, Murali M.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

1. Overview of Autoimmune Disorders and Immunotherapy
2. The Immunopathogenesis of Autoimmune Diseases
3. Monoclonal Antibodies in Autoimmune Disease Treatment
4. Immune Checkpoint Inhibitors in Autoimmunity
5. T-cell Modulation Therapies
6. Cytokine Targeting Therapies
7. B-cell Depletion Strategies
8. Adoptive Cell Transfer and Regulatory T Cells
9. Immunomodulatory Agents and Small Molecules
10. Personalized Immunotherapy Approaches
11. Immunotherapy in Specific Autoimmune Diseases
12. Future Directions and Emerging Therapies in Immunotherapy for Autoimmune Disorders
13. Regulatory and Ethical Considerations in Autoimmunotherapy Application

Über Autor(innen)

Yallapu, Murali M.
Dr. Murali Yallapu is a tenured Associate Professor at the University of Texas Rio Grande Valley's School of Medicine, specializing in Immunology, Microbiology, and Oncology and a member of the South Texas Center of Excellence in Cancer Research. Dr. Yallapu received the "Prof. A. Kameswara Rao's Gold Medal-1999" and completed postdoctoral training in materials science, drug delivery, nanomedicine, and cancer biology at institutions including the Cleveland Clinic and the University of Nebraska Medical Center. Before joining UTRGV, he was an Assistant Professor at the University of Tennessee Health Science Center. Dr. Yallapu serves on editorial boards for various journals related to drug delivery, nanotechnology, and cancer, and is an ad-hoc reviewer for the NIH and other funding agencies. He has published over 190 peer-reviewed articles and reviews. His primary research focuses on developing nanomaterials for enhanced therapeutic potential and cancer immunotherapy.

Apostolopoulos, Vasso
Professor Vasso Apostolopoulos is a Distinguished Professor at RMIT University, Australia. She received her PhD in immunology in 1995 from the University of Melbourne and the Advanced Certificate in Protein Crystallography from Birkbeck College, University of London. Professor Vasso Apostolopoulos is a world-renowned researcher who has been recognized with over 100 awards for the outstanding results of her research. She has published over 500 research publications, 8 books, and 33 book chapters, is a sought-after keynote speaker at conferences, is an inventor on 21 patents, and has over 22,000 citations.

Bandaru, Nagaraju
Nagarau Bandaru completed his B. Pharm (2011) and M. Pharm (2013) in Pharmacology from Shri Vishnu College of Pharmacy, Bhimavaram, and earned his PhD (2021) from Acharya Nagarjuna University, Guntur, AP, India. With 10 years of teaching experience, he has published 48 research and review papers, 6 patents, and 8 books. He has presented at numerous national and international seminars and conferences and delivered guest lectures at various Indian universities. His accolades include the Best Teacher award from K L University, Best Researcher, Young Scientist, and Distinguished Alumni awards from Shri Vishnu College of Pharmacy. He has received fellowships such as GPAT AICTE and CSIR NEIST summer research fellowship. His research focuses on Neuropharmacology. He has guided many M. Pharm and B. Pharm student projects and is an approved Ph.D. supervisor at Sandip University and K L University. He has also completed 4 NGO projects and secured funded grants.

Singh, Arun Kumar
Arun Kumar Singh is an Assistant Professor in the Department of Pharmacy at University School of Pharmaceutical Sciences, Rayat Bahra University V.P.O. Sahauran, India. He completed his M.Pharm in Pharmaceutics from Galgotias University, Greater Noida. His research interests include nano-formulation, blockchain, IoT, machine learning, artificial intelligence, big data analytics, cancer biology, and neuroscience. He has contributed to academic books and book chapters and has published review articles in the areas of pharmaceutical sciences and healthcare technology. His work focuses on interdisciplinary approaches integrating pharmaceutical research with emerging digital and computational technologies.

Pareek, Ashutosh
Dr. Ashutosh Pareek, Professor at Banasthali Vidyapith with over 15 years of experience in pharmaceutical sciences, holds gold medals for his Master's and Bachelor's degrees in Pharmacy. Dr. Pareek specializes in neuropharmacology and innovative drug delivery systems, focusing on neurodegenerative disorders, cancer, and autoimmune diseases. His research includes developing advanced drug delivery systems for immunomodulators like naringenin. Dr. Pareek leads a research team working on these critical health issues and has published over 45 research papers and authored five technical books. He holds an international formulation patent and has received numerous awards, including the Zee National Achievers Award 2023. His work is funded by national and international agencies such as ICMR, DST-SERB, DBT, the American Association of Pharmaceutical Scientists, and the International Brain Research Organization. He serves as a Review Editor for Frontiers in Pharmacology and Frontiers in Oncology and reviews for leading journals by Elsevier, Springer, and Bentham.