Smart Pharmaceutical Microneedles

Revolutionizing Soft Tissue Infection Control
1. Auflage 2027
ISBN: 978-1-041-26786-7
Verlag: Taylor & Francis Ltd

Buch, Englisch, 280 Seiten, Format (B × H): 210 mm x 280 mm

This book presents a comprehensive overview of smart microdevice-based technology emphasising on polymeric microneedles and their integration with nanotechnology for advanced transdermal drug delivery. It covers the principles of microneedle technology, design and fabrication strategies, drug encapsulation and controlled release systems, and the role of nanocomposites in enhancing therapeutic efficacy. The chapters explore nanotechnology-enabled microneedles as a promising theranostic toolbox for addressing soft tissue infections and discuss their potential to overcome the limitations of conventional drug delivery methods. It also highlights the translational potential of these technologies, emphasizing their ability to bridge the gap between laboratory research and clinical application for improved patient care.

Key Features:

- Explains foundational principles of microneedle technology and its evolution as a next-generation drug delivery platform

- Details design and fabrication methodologies for smart polymeric microneedles, including integration with nanotechnology

- Covers drug encapsulation and controlled release strategies to optimize therapeutic outcomes

- Highlights nanocomposite hydrogel microneedles as an innovative theranostic tool for soft tissue infections

- Presents translational potential of microneedle-assisted systems, emphasizing their role in bridging laboratory research with clinical applications

The book is useful for researchers of pharmaceutical sciences, biomedical engineering, and nanotechnology.

Zielgruppe

Professional Reference

Autoren/Hrsg.

Singh, Sudarshan

Mohite, Popat

Puri, Abhijeet Vishnu

Datta, Deepanjan

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie

Inhaltsverzeichnis

Chapter 1: Introduction to Microneedle Technology. Chapter 2: Soft Tissue Infections: A Clinical and Therapeutic Challenge. Chapter 3: Nanotechnology-infused microdevices: Bridging scales for smarter therapeutics. Chapter 4: Engineering Microneedles: Fabrication Strategies and Technological Advances. Chapter 5: Smart release from microneedles: Engineering drug encapsulation for therapeutic control. Chapter 6: Polymeric Microneedles: Unlocking Skin Barrier for Therapeutic Delivery. Chapter 7: Microneedle Arrays Combined with Nanomedicine Approaches for Transdermal Delivery of Therapeutics. Chapter 8: Advances in Microneedle technology for topical drug delivery and skin-targeted therapies. Chapter 9: Microneedle-based devices for point-of-care infectious disease diagnostics. Chapter 10: Nanocomposite Hydrogel Microneedles: A Theranostic Toolbox for Soft Tissue Infections. Chapter 11: Microneedle Technologies: Bridging Precision Drug Delivery with Advanced Wound Healing. Chapter 12: Additive Manufactured Microneedles in the Management of Soft-Tissue Infections. Chapter 13: Microneedle Technologies: Safety Profiles, Clinical Trials, and Translational Studies with compliance. Chapter 14: Microneedles in Oncology-Associated SSTIs: Tailoring Delivery of Immunocompromised Hosts Chapter 15: Challenges and future directions in microneedle technology in the management of soft-tissue infection.

Über Autor(innen)

Sudarshan Singh is presently working at SNJB’s SSDJ College of Pharmacy, MS, India, as an Associate Professor. He has authored ten technical textbooks for pharmacy graduate students and has edited four professional books published along with several peer-reviewed book chapters. He has published more than 150 research and review papers in reputed peer-reviewed journals. Dr. Singh has presented numerous papers and participated as a resource person in international and national conferences. He has been ratified and approved by Pacific University, Rajasthan, India, as a PhD guide and has five registered patents to his credit. He serves as an editorial board member and reviewer for various international journals. Dr. Singh has eleven years of teaching experience in undergraduate and postgraduate pharmacy courses, coupled with more than six years of research and development experience. He has guided several undergraduate and postgraduate students in their project work and, during his postdoctoral research at Prince of Songkhla University, Thailand, co-supervised four doctoral students. He is a life member of professional bodies such as the Society of Pharmacovigilance, India, and is a registered pharmacist with the State Pharmacy Council of Chhattisgarh, India. He has received several research grants from the Government of Gujarat and Savitribai Phule Pune University, Maharashtra, as well as travel grants from the Indian Council of Medical Research, New Delhi, and the Centre for International Cooperation in Science, Tamil Nadu, India.

Popat Mohite is currently working as an Associate Professor and Head of the Department of PG Studies at AET’s St. John Institute of Pharmacy and Research, Palghar. He has 18 years of teaching and research experience and has several national and international journal publications to his credit, along with research grants from the University of Pune. He has presented research papers at numerous national and international conferences and has guided more than 38 postgraduate students. He is an accomplished researcher with an impressive publication record comprising 195 research and review articles, including 38 review papers published in reputed national and international journals. His scholarly contributions have received wide recognition, reflected by more than 2848 Google Scholar citations, a cumulative journal impact factor exceeding 371.50, a Google Scholar h-index of 29, an i10-index of 65. His research interests encompass pharmaceutical chemistry, drug design, nanotechnology-based drug delivery systems, phytopharmaceuticals, heterocyclic chemistry, molecular docking, and pharmaceutical analysis. He holds two published patents and serves as a reviewer and editorial board member for several journals. He is a lifetime member of IPA, APTI, and ISTE and has been awarded the Young Researcher Award. His research interests include synthesis and biological evaluation, QSAR studies, formulation, surface functionalization of polymers, and analytical method development and validation.

Abhijeet Vishnu Puri is currently serving as Head of Department and Associate Professor at St. John Institute of Pharmacy and Research, Palghar, with 14 years of teaching experience in Pharmacognosy. He earned his PhD from the University of Mumbai and has published several research and review papers in peer-reviewed national and international journals. He has authored multiple book chapters and received research grants from the University of Mumbai. He serves as a reviewer for several reputed international journals and has presented research papers at numerous national and international conferences. In 2023, he was awarded Best Oral Presentation at the 72nd Indian Pharmaceutical Congress, Nagpur. His research focuses on nano-enabled metallic nanoparticles, natural polymers, formulation and evaluation of herbal preparations, and standardization of polyherbal formulations. He is also a life member of the Indian Society for Technical Education (ISTE), Association of Pharmaceutical Teachers of India (APTI), Indian Pharmaceutical Association (IPA), and the Maharashtra State Pharmacy Council, Mumbai.

Deepanjan Datta is an Assistant Professor at the Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), India, with over eight years of academic, research, and industrial experience in pharmaceutical sciences and advanced drug delivery systems. His research focuses on biomaterials, microneedles, transdermal and topical drug delivery, peptide therapeutics, and biomedical devices. He has authored numerous national and international peer-reviewed publications and has secured research funding from prestigious agencies, including the Indian Council of Medical Research (ICMR), Manipal Academy of Higher Education, the Anusandhan National Research Foundation (ANRF), and the BioNEST Incubation Centre at NIPER Guwahati. He has notable scientific contributions include the development of peptide-loaded microneedle contact lenses, innovative bioadhesive biomedical devices for enhanced transdermal peptide delivery, and peptide-based gel formulations for the Defence Research and Development Organisation (DRDO). In recognition of his contributions to controlled release and drug delivery technologies, he received the Young Scientist Award from the Controlled Release Society (CRS) in 2019. Prior to joining academia, he worked as a Formulation and Research Scientist at Dr. Reddy's Laboratories, Hyderabad, in the topical and transdermal research division. He is also the inventor of an international PCT patent, Topical Skin Care Applications (WO2018198039A1), and actively contributes to the scientific community.