Current Developments in Biotechnology and Bioengineering: Synthetic Biology, Cell Engineering and Bioprocessing Technologies

Erscheinungsjahr 2018
ISBN: 978-0-444-64085-7
Verlag: ELSEVIER

Buch, Englisch, 442 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 753 g

Current Developments in Biotechnology and Bioengineering: Synthetic Biology, Cell Engineering and Bioprocessing Technologies covers the current perspectives and outlook of synthetic biology in the agriculture, food and health sectors. This book begins with the basics about synthetic biology and cell engineering, and then explores this in more detail, focusing on topics like applications of synthetic biology, industrial bioprocesses, and future perspectives. Information on cell engineering is also presented, and manipulation in endogenous metabolic network is studied alongside advanced topics such as fine tuning of metabolic pathways, de novo biosynthetic pathway design, enzyme engineering targeted to improved kinetics and stability, and potential applications of the novel biological systems in bioprocess technology to achieve the production of value-added compounds with specific biological activities.

Zielgruppe

<p>The intended audience will be graduate and post-graduate students, doctoral fellows, researchers, mentors, teachers, and specific trainees in the area of biochemical engineering /biotechnology</p>

Autoren/Hrsg.

Singh, Sudhir P.

Pandey, Ashok

Du, Guocheng

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie

Inhaltsverzeichnis

Section 1: Synthetic biological systems; Concepts and molecular toolkits1. Basics and roots of synthetic biology2. Advances in cell-free biosynthetic technology3. Genome engineering tools in plant synthetic biology

Section 2: Genome engineering and biosynthetic repertoires4. Constructing synthetic pathways in plants: Strategies and tools5. Synthetic regulatory tools to engineer microbial cell factories for chemical production6. A CRISPR technology and biomolecule production by synthetic biology approach

Section 3: Biocatalyst engineering and industrial bioprocesses7. Enzyme engineering and industrial bioprocess8. Synthetic biology for production of commercially important natural product small molecules9. Biosynthetic technology and bioprocess engineering

Section 4: Applications of Synthetic Biology10. Regulated gene expression by synthetic modulation of the promoter architecture in plants11. Biosynthesis of high-value amino acids by synthetic biology12. Synthetic biology approaches for the production of 2-butanol13. Synthetic biology approaches for the production of isoprenoids in Escherichia coli14. System metabolic engineering applications in Corynebacterium crenatum for L-Arginine production

Section 5: Future perspectives of synthetic metabolism15. Synthetic metabolism and its significance in agriculture 16. Applications and future perspectives of synthetic biological systems

Über Autor(innen)

Du, Guocheng
Professor Guocheng Du is the Dean of School of Biotechnology, Jiangnan University, China. He is the distinguished professor of Changjiang Scholars, Ministry of Education, China. His current main research focus is on bioprocess engineering and metabolic engineering. He has about 200 publications/communications, which include 52 patents, 8 books, 160 original and review papers, etc. He won two Second Prizes of State Science and Technology Award in 2006 and 2012, respectively. He has been conferred Honorary Doctorate degree from Jiangnan University, China. Professor Guocheng Du is deputy director in the committee of biochemical engineering modelling and control, Chinese Society for Microbiology, and deputy director of Beer Branch, China Alcoholic Drinks Industry Association. He is the associate editor of Journal of the Science of Food and Agriculture and the editorial board member of Bioresource Technology.

Pandey, Ashok
Prof. Ashok Pandey is currently Executive Director, Centre for Energy and Environmental Sustainability-India, Lucknow. His major research and technological development interests are industrial and environmental biotechnology and energy biosciences, focusing on biomass to biofuels and chemicals, waste to wealth and energy, etc.

Singh, Sudhir P.
Dr. Sudhir P. Singh obtained his Ph.D. in the year 2011 from University of Lucknow, India. Subsequently, he worked as research associate and then as Project Scientist at National Agri-Food Biotechnology Institute, Mohali, India. He joined Center of Innovative and Applied Bioprocessing, Mohali, India in 2015, as Scientist-C. He has been working in the area of molecular biology, and synthetic biology. In the area of plant molecular biology his some of the significant contribution are: development stringently regulated expression systems for inducing male sterility and male sterility-fertility restoration system in plants, investigation of tissue and cell-type specific distribution pattern of mineral nutrients in wheat grains and its possible impacts on bioavailability, the first transcriptome analysis and molecular insights into seed development biology in the fruit crops, Custard apple and Litchi, and secondary metabolite pathways in Rose-scented geranium, development of approaches based on Rootstock-scion or modified viral genome based long distance signalling as possible strategies for inducing trait modification such as seedlessness. His current research focus is towards development of synthetic biocatalysts for biotransformation of agro-industrial by-products and residues into value added biomolecules. In the area of biosynthetic technology his some of the significant contribution are: development of novel approaches for transformation of agro-industrial residues and bioresources into functional and prebiotic biomolecules, development of a novel strategy for the improvement of operational stability of D-psiose 3-epimerase enzyme. He has been interested in employing the basic knowledge for translational research. He has published 33 research papers in peer reviewed journals, 4 review articles/book chapters, and 4 patents to his credit.