Biochemistry and Molecular Biology

6. Revised Auflage 2018
ISBN: 978-0-19-876811-1
Verlag: Oxford University Press

Buch, Englisch, 640 Seiten, Format (B × H): 274 mm x 218 mm, Gewicht: 1382 g

Now in its sixth edition, Biochemistry and Molecular Biology provides the perfect balance between detail and conceptual understanding. Maintaining the much-praised clarity of previous editions, this edition incorporates both new techniques and pivotal discoveries in a succinct, easy-to-digest way, using updated figures and diagrams to help explain complex processes.

Updated content on the manipulation of DNA and genes reflects the rapid introduction of new methods in contemporary research, and incorporates up-to-date discussions of recent developments such as gene editing. Chapter summaries are logically laid out, forming bulleted lists which provide students with a consolidation of difficult concepts and progressively guide them through the specifics whilst keeping the big picture in mind. Additional 'find out more' sections provide helpful problem-solving support and the further reading is divided into types to cater for broader learning needs.

With an integrated approach covering both biochemistry and molecular biology, complemented by frequent diagrams and clear explanations, and all presented in a wider cellular context, this text is the perfect introduction for any student new to the subject.

Online Resources:

The online resources to accompany this text include:

For registered adopters of the book:

· Figures from the book available to download

For students:

· Further reading organised by chapter
· An extensive bank of multiple-choice questions to support self-directed learning
· Links to 3D molecular structures in Protein Data Bank

Autoren/Hrsg.

Snape, Alison

Papachristodoulou, Despo

Elliott, William H.

Elliott, Daphne C.

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Inhaltsverzeichnis

- Part 1: Basic concepts of life

- 1: The basic molecular themes of life

- 2: Cells and viruses

- 3: Energy considerations in biochemistry

- Part 2: Structure and function of proteins and membranes

- 4: The structure of proteins

- 5: Methods in protein investigation

- 6: Enzymes

- 7: The cell membrane and membrane proteins

- 8: Muscle contraction, the cytoskeleton, and molecular motors

- Part 3: Metabolism and Nutrition

- 9: General principles of nutrition

- 10: Food digestion, absorption and distribution to the tissues

- 11: The storage fuels: Mechanisms of transport, storage, and mobilization of carbohydrate and fat

- 12: Principles of energy release from food

- 13: Glycolysis, the TCA cycle, and the electron transport system

- 14: Energy release from fat

- 15: An alternative pathway of glucose oxidation: The pentose phosphate pathway

- 16: Synthesis of glucose (gluconeogenesis)

- 17: Synthesis of fat and related compounds

- 18: Nitrogen metabolism: amino acid metabolism

- 19: Nitrogen metabolism: nucleotide metabolism

- 20: Mechanisms of metabolic control and their applications to metabolic integration

- 21: Raising electrons of water back up the energy scale: photosynthesis

- Part 4: Information storage and utilization

- 22: The genome

- 23: DNA synthesis, repair and recombination

- 24: Gene transcription

- 25: Protein synthesis and controlled protein breakdown

- 26: Control of gene expression

- 27: Protein sorting and delivery

- 28: Manipulating DNA and genes

- Part 5: Cells and tissues

- 29: Cell signalling

- 30: The cell cycle, cell division, cell death and cancer

- Part 6: Protective mechanisms against disease

- 31: Blood clotting, xenobiotic metabolism, and reactive oxygen species

- 32: The immune system

Über Autor(innen)

Dr Despo Papachristodoulou is a Reader in Biochemistry and Medical Education at Kings College London. Her interests include metabolism and nutrition, obesity, diabetes and diabetic complications, medical education and curriculum development. Dr Papachristodoulou has a long experience of teaching Biochemistry and Nutrition to Medical, Dental and Biomedical undergraduates and is lead of the Professional/Graduate Entry to Medicine programme at Kings College.

Dr Alison Snape is Senior Lecturer and Head of the Teaching Department of Biochemistry at King's College London. Her interests include regulation of gene expression and differentiation in early embryonic development. Dr Snape has extensive experience of teaching biochemistry and molecular biology to undergraduates and organises modules that are taken by first year students in bioscience and nutrition programmes.