Protein Structure Prediction

A Practical Approach
Erscheinungsjahr 1997
ISBN: 978-0-19-963496-5
Verlag: OUP Oxford

Buch, Englisch, 318 Seiten, Print PDF, Format (B × H): 156 mm x 234 mm, Gewicht: 488 g

The three-dimensional structure of proteins is a key factor in their biological activity. There is an increasing need to be able to predict the structure of a protein once its amino-acid sequence is known; this book presents practical methods of achieving that ambitious aim, using the latest computer modelling algorithms.

Autoren/Hrsg.

Sternberg, M.

Sternberg, Michael J. E.

Fachgebiete

• Mathematik | Informatik EDV | Informatik Professionelle Anwendung Computersimulation & Modelle, 3-D Graphik
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Naturwissenschaften Biowissenschaften Proteinforschung

Inhaltsverzeichnis

- 1.: Protein structure prediction - principles and approaches

- 2.: Protein sequence alignment and database scanning

- 3.: Identification of protein sequence motifs

- 4.: Prediction of secondary structure

- 5.: Prediction of transmembrane protein topology

- 6.: Comparative modelling of proteins

- 7.: Antibody combining sites: structure and prediction

- 8.: Protein folds and their recognition from sequence

- 9.: The combinatorial approach

- 10.: Modelling protein conformation by molecular mechanics and dynamics

- 11.: Docking ligands to proteins

- 12.: The prediction challenge