Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing

1. Auflage 2022
ISBN: 978-3-527-34769-8
Verlag: WILEY-VCH

Buch, Englisch, 400 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 879 g

Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing

Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field

With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry.

In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products.

A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: - Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines
- Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems
- Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing
- In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification

Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.

Autoren/Hrsg.

Subramanian, Ganapathy

Subramanian, G.

Fachgebiete

• Naturwissenschaften Chemie Analytische Chemie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie

Inhaltsverzeichnis

Part I - Continuous Biomanufacturing
1. Strategies for Continuous Processing in Microbial Systems
2.Control of Continuous Manufacturing Processes for Production of Monoclonal Antibodies
3.Artifical Intelligence and the Control of Continuous Manufacturing
 
Part II - Intensified Biomanufacturing
4. Bioprocess Intensification: Technologies and Goals
5. Process Intensification Based on Disposable Solutions as First Step toward Continuous Processing
6. Single-Use Continuous Manufacturing and Process Intensification for Production of Affordable Biological Drugs
 
Part III - Digital Biomanufacturing
7. Process Intensification and Industry 4.0: Mutually Enabling Trends
8. Consistent Value Creation from Bioprocess Data with Customized Algorithms: Opportunities Beyond Multivariate Anaysis
9. Digital Twins for Continuous Biologics Manufacturing
10. Regulatory and Quality Considerations of Continuous Bioprocessing
 

Über Autor(innen)

Dr. Ganapathy Subramanian is a biotechnology consultant with over 30 years of experience in industry and academia, encompassing the application and development of processing, purification methodologies, and chromatographic systems for large scale use in environmental science, food science, perfumery, cosmetics, and pharmaceuticals. He has also taught extensively in the area of food and medical technology.
A chemistry graduate from Madras, India, Dr. Subramanian was awarded his doctorate from the University of Glasgow for work on natural products. His main research interests lie in the utilization of natural material separation processes and bioconversions.
Dr. Subramanian has written and edited a number of books and articles in the field of biotechnology. For the last 15 years, he has been organizing conferences promoting the integration and sharing of knowledge between academia and industry.