Structure and Function of Glutathione S-Transferases

1. Auflage 1993
ISBN: 978-0-8493-4582-1
Verlag: Taylor & Francis

Buch, Englisch, 336 Seiten, Format (B × H): 156 mm x 234 mm, Gewicht: 725 g

Structure and Function of Glutathione S-Transferases provides some of the latest information available on a variety of structural and functional components of glutathione S-transferases, a family of isozymes involved in many endogenous and exogenous functions in cells. Molecular studies presented in the book focus on the regulation of these enzymes and identify important response elements. X-ray crystallographic structures show detailed information on the structural aspects of these proteins. Metabolism of a number of carcinogens and drugs is covered in detail, and the role that these enzymes play in governing drug resistance at the preclinical and clinical levels is discussed. The book will be excellent for biochemists, pharmacologists, oncologists, experimental therapeutic specialists, and others interested in glutathione S-transferases.

Autoren/Hrsg.

Tew, Kenneth D.

Pickett, Cecil B.

Mantle, Timothy J.

Mannervik, Bengt

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Infektionskrankheiten
• Naturwissenschaften Biowissenschaften Enzymologie

Inhaltsverzeichnis

Functions of GST. Molecular Enzymology. Gene Expression. Resistance to Drugs and Oxidative Stress.

Über Autor(innen)

Kenneth D. Tew, Cecil B. Pickett; Timothy J. Mantle; Bengt Mannervik