Carbon Monoxide and Cardiovascular Functions

1. Auflage 2001
ISBN: 978-0-8493-1041-6
Verlag: Taylor & Francis Inc

Buch, Englisch, 336 Seiten, Format (B × H): 163 mm x 241 mm, Gewicht: 608 g

Akin to nitric oxide, carbon monoxide (CO) was initially viewed as a pure toxic gas, yet it has been recently demonstrated to be an important endogenous molecule of gas that has profound physiological and pathophysiological effects on the cardiovascular system. In spite of the growing understanding achieved in this field, until now a comprehensive book summarizing the extraordinary advances in the research of the cardiovascular effects of CO has not been available.

Carbon Monoxide and Cardiovascular Functions responds to the vexing challenges and exciting opportunities that confront researchers and clinicians studying the biological roles of CO in the cardiovascular system. This book presents many never-before-published results including the first case of human CO deficiency. It also discusses disorders where the cardiovascular effects of CO might have been altered, including hypertension, diabetes, stroke, and ischemic heart damage.

A product of the collected knowledge of internationally respected scientists, this book serves as a standard reference summarizing recent developments, scientific controversies, and future directions in the study of the biological actions of CO on the cardiovascular system. By covering both ancient and state-of-the-art methodologies in great detail, Carbon Monoxide and Cardiovascular Functions, affords a rapid mastery of the powerful new advances in CO study.

Zielgruppe

Professional and Professional Reference

Autoren/Hrsg.

Wang, Rui

Fachgebiete

• Naturwissenschaften Chemie Chemie Allgemein Chemische Labormethoden, Stöchiometrie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie
• Naturwissenschaften Chemie Chemie Allgemein Chemometrik, Chemoinformatik
• Naturwissenschaften Chemie Chemie Allgemein Toxikologie, Gefahrstoffe, Sicherheit in der Chemie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie

Inhaltsverzeichnis

CARBON MONOXIDE AND PHYSIOLOGICAL FUNCTIONS OF THE CARDIOVASCULAR SYSTEM: The Physiological Role of Carbon Monoxide Derived from Heme Oxidation Catalysed by Heme Oxygenase. Carbon Monoxide-Induced Vasorelaxation and the Underlying Mechanisms. Carbon Monoxide and Vascular Smooth Muscle Cell Growth. Signal Transduction Pathways Involved in CO-Induced Vasodilation. Carbon Monoxide, Vascular Contractility, and K+ Channels. Nitric Oxide and the Heme Oxygenase/Carbon Monoxide System. Developmental Biology of Heme Oxygenase and Carbon Monoxide in the Cardiopulmonary System. Carbon Monoxide Signaling in the Heart. CARBON MONOXIDE AND PATHOPHYSIOLOGY OF THE CARDIOVASCULAR SYSTEM: The Heme-Heme Oxygenase-Carbon Monoxide System and Hypertension. Carbon Monoxide and Cardiovascular Inflammation. Human HO-1 Deficiency and Cardiovascular Dysfunction. The Roles of Carbon Monoxide in the Pathogenesis of Diabetes and Its Vascular Complications. Selective Increase in Human Heme Oxygenase-1 Gene Expression Attenuates Development of Hypertension and Increases Body Growth in Spontaneously Hypertensive Rats. TECHNIQUES USED IN CARBON MONOXIDE RESEARCH: Studies on the Development of Carbon Monoxide-Releasing Molecules. Sources, Sinks, and Measurement of Carbon Monoxide.

Über Autor(innen)

Rui Wang