Investigating Biological Systems Using Modeling

Strategies and Software
Erscheinungsjahr 1998
ISBN: 978-0-12-736740-8
Verlag: William Andrew Publishing

Buch, Englisch, 382 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 900 g

Investigating Biological Systems Using Modeling describes how to apply software to analyze and interpret data from biological systems. It is written for students and investigators in lay person's terms, and will be a useful reference book and textbook on mathematical modeling in the design and interpretation of kinetic studies of biological systems. It describes the mathematical techniques of modeling and kinetic theory, and focuses on practical examples of analyzing data. The book also uses examples from the fields of physiology, biochemistry, nutrition, agriculture, pharmacology, and medicine.

Zielgruppe

AUDIENCE: Graduate students and professionals in the fields of medicine, physiology, biochemistry, biomathematics, pharmacology, agricultural systems, nutrition, and animal science.

Autoren/Hrsg.

Wastney, Meryl E.

Patterson, Blossom H.

Linares, Oscar A.

Greif, Peter C.

Boston, Raymond C.

Fachgebiete

• Geowissenschaften Umweltwissenschaften Umweltüberwachung, Umweltanalytik, Umweltinformatik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Physiologie
• Geowissenschaften Umweltwissenschaften Angewandte Ökologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe

Inhaltsverzeichnis

Introduction:

What is Modeling?
The Steps in Building a Model.
The Difference Between Building a Model and Using a Model.
Why Model Biological Systems?
Modeling Software:

Review of Software.
WinSAAM.
Concepts and Tools of Modeling:

Building Models in Sections.
Techniques and Tools to Facilitate Model Development.
Strategies for Modeling Biological Systems:

Experimental Design and Data Collection.
Starting Modeling and Developing a Model.
Rejecting Hypotheses and Accepting a Model.
Model Summarization.
Multiple Studies Analysis.
Information in the Model.
Errors in Compartmental Modeling.
Testing Robustness: Sensitivity, Identifiability, and Stability.
Evaluating and Using Published Models:

Why Use a Published Model?
Reviewing and Summarizing Published Models.
The Model Translation Process.
Verification and Validation.
Using the Model.
A Library of Models.
Subject Index.
Appendices.

Über Autor(innen)

Wastney, Meryl E.
Meryl Wastney is an Associate Professor in the Department of Pediatrics and the Department of Biomathematics and Biostatistics at the Georgetown University Medical Center in Washington D.C. She received her Ph.D. in biochemistry from Lincoln College at the University of Canterbury in New Zealand. She was a Fogarty Fellow in the Laboratory of Mathematical Biology, NCI, NIH, Bethesda, Maryland for three years and joined the Department of Pediatrics at Georgetown University in 1983. She is the author of 30 articles and has presented over 40 invited lectures and workshops on modeling biological systems.