Wiseman | Principles of Biotechnology | Buch | 978-0-903384-60-5 | www.sack.de

Buch, Englisch, 211 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 332 g

Wiseman

Principles of Biotechnology


Erscheinungsjahr 1990
ISBN: 978-0-903384-60-5
Verlag: Springer

Buch, Englisch, 211 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 332 g

ISBN: 978-0-903384-60-5
Verlag: Springer


The first edition of this book appeared in 1983, and provided the first easily-accessible account of the state of biotechnology at a level suitable for advanced undergraduates and postgraduates. In this new edition, specialists in biotechnology at the University of Surrey have again collaborated with industrial experts to provide authoritative interdisciplinary coverage of an ever-expanding field. The revision of the text reflects the rapid advances made in many of the fields which go to make up biotechnology-ranging from the molecular to the process plant level. Biotechnology is an applied science, and this book relates theory to application by placing the basic advances in the context of commercial applicability and process optimization. For those wishing to explore the literature further, references to up-to-date reviews and original research publications are provided. Special thanks are due not only to the contributors, but to all those who have helped in the planning of this book.AW v Background to authors C. Bucke is Principal Lecturer in the School of Biotechnology, Polytechnic of Central London, and was previously Programme Manager Biotechnology at Tate & Lyle Group Research and Development. His research interests include the production and use of immobilized biocatalysts, the use of enzymes in the synthesis of novel bisaccharides and polysaccharides and the use of enzymes in extreme environments. He is Scientific Co-ordinator of the Institute for Biotechnological Studies, Department of Trade and Industry 'Extended use of Biocatalysts' Programme.

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1 Features of biotechnology and its scientific basis.- 1.1 Introduction.- 1.2 Interrelationships between microorganisms and enzymes.- 1.3 Success in biotechnology.- 2 Application of the principles of industrial microbiology to biotechnology.- 2.1 Introduction.- 2.2 Primary metabolism.- 2.3 Secondary metabolism.- 2.4 Primary metabolites in industrial biotechnology.- 2.5 Secondary metabolites in biotechnology.- 3 Application of the principles of microbial genetics to biotechnology.- 3.1 Control mechanisms in microorganisms.- 3.2 Manipulations in vivo.- 3.3 Manipulations in vitro.- 4 Application of the principles of fermentation engineering to biotechnology.- 4.1 The fermenter.- 4.2 General design principles.- 4.3 Heat transfer.- 4.4 Mixing.- 4.5 Oxygen supply in fermenters.- 4.6 Scale-up in biotechnology.- 4.7 Fermentation processes in biotechnology.- 4.8 Summary.- 5 Application of the principles of enzymology to biotechnology.- 5.1 Features of enzymes in relation to biotechnology.- 5.2Applications of enzymes in biotechnology.- 6 The biotechnology of enzyme isolation and purification.- 6.1 Introduction.- 6.2 Enzyme sources.- 6.3 Release of enzymes from cells.- 6.4 Primary clarification of the soluble enzyme.- 6.5 Concentration.- 6.6 Enzyme purification—chromatography.- 7 The application of immobilized enzymes, immobilized cells and biochemical reactors in biotechnology—principles of enzyme engineering.- 7.1 Introduction.- 7.2 The application of biological catalysts.- 7.3 Types of enzymic catalyst and commercial applications.- 7.4 Enzyme reactors.- 7.5 Conclusions.



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