Magnetic Nanoparticles in Nanomedicine

Erscheinungsjahr 2024
ISBN: 978-0-443-21668-8
Verlag: Elsevier Science

Buch, Englisch, 542 Seiten, Format (B × H): 151 mm x 226 mm, Gewicht: 1000 g

Magnetic Nanoparticles in Nanomedicine provides readers with the fundamental theories and principles of magnetic materials, the synthesis and surface functionalization strategies of MNPs, and the standard techniques for characterizing physicochemical properties of MNPs. Other sections review MNP-based therapies such as magnetic hyperthermia therapy, drug/gene delivery, and magnetic neurostimulation and cover MNP-based in vitro and in vivo disease diagnosis, respectively, including techniques such as magnetoresistive (MR), nuclear magnetic resonance (NMR), magnetic particle spectroscopy (MPS) biosensing platforms, magnetic resonance imaging (MRI), and magnetic particle imaging (MPI).

Final chapters address biocompatibility and safety issues in applying MNPs to in vivo biomedical applications, including coverage of the toxicity of MNPs to human tissues, the immune responses of the human body to these particles, as well as blood circulation time of MNPs.

Autoren/Hrsg.

Wu, Kai

Wang, Jian-Ping

Fachgebiete

• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde Materialwissenschaft: Biomaterialien, Nanomaterialien, Kohlenstoff

Inhaltsverzeichnis

Section I. Magnetic Nanoparticles (MNPs): Synthesis, Functionalization and Characterization
1. Basics of Magnetic Materials and Magnetism
2. Micromagnetic Simulation
3. Current Methods for Synthesis and Surface Modifications of MNPs
4. Current Characterization Techniques for MNPs

Section II. MNPs for Therapy
5. MNPs for Hyperthermia Therapy
6. MNPs for Drug/Gene Delivery
7. MNPs for Neurostimulation

Section III. MNPs for In Vitro Disease Diagnosis
8. Magnetoresistive (MR) Biosensor
9. Nuclear magnetic resonance (NMR) Biosensor
10. Magnetic Particle Spectroscopy (MPS) Biosensor
11. Magnetic Separation Assisted Diagnosis

Section IV. MNPs for In Vivo Disease Diagnostic Imaging
12. Magnetic Resonance Imaging (MRI)
13. Magnetic Particle Imaging (MPI)

Section V. Biocompatibility and Immunotoxicity of MNPs
14. Immunotoxicity and Safety Considerations
15. Cellular Uptake and Blood Circulation Time of MNPs

Über Autor(innen)

Wu, Kai
Kai Wu is an assistant professor in the Department of Electrical & Computer Engineering at Texas Tech University in Lubbock, TX, United States. His research interests include the synthesis of magnetic nanomaterials, fabrication of magnetic nanodevices, micromagnetic simulation, development of point-of-care medical devices based on magnetic biosensors, and magnetic neuron stimulation and recording.

Wang, Jian-Ping
Jian-Ping Wang is a professor in the Department of Electrical and Computer Engineering at the University of Minnesota, Minneapolis, MN, United States. His research interests include nanomagnetism and quantum spintronics with a focus on searching, fundamentally understanding, and fabricating novel magnetic materials and quantum spintronic devices.