Buch, Englisch, Band 1888, 315 Seiten, HC runder Rücken kaschiert, Format (B × H): 183 mm x 260 mm, Gewicht: 816 g
Reihe: Methods in Molecular Biology
Methods and Protocols
Buch, Englisch, Band 1888, 315 Seiten, HC runder Rücken kaschiert, Format (B × H): 183 mm x 260 mm, Gewicht: 816 g
Reihe: Methods in Molecular Biology
ISBN: 978-1-4939-8890-7
Verlag: Springer
Cutting-edge and thorough, Systems Chemical Biology: Methods and Protocols is a valuable resource for novice or expert scientists and researchers trying to initiate or continue their chemical biology studies at a systems level.
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Weitere Infos & Material
1. PREDECT protocols for complex 2D/3D cultures.- 2. Phenotypic Screening using Mouse and Human Stem Cell-based Models of Neuroinflammation and Gene Expression Analysis to Study Drug Responses.- 3. Quantitative, Real-Time Measurements of Intracellular Target Engagement Using Energy Transfer.- 4. Target Engagement of Small Molecules – Thermal Profiling Approaches on Different Levels.- 5. Visualizing Bio-active Small Molecules by Alkyne-tagging and Slit-scanning Raman Microscopy.- 6. The Cell Painting Assay as a screening tool for the discovery of bioactivities in new chemical matter.- 7. Proteomic Profiling for Target Identification of Biologically Active Small Molecules using 2-D DIGE.- 8. Examining Cellular Responses to Kinase Drug Inhibition through Phosphoproteome Mapping of Substrates.- 9. CRISPR/Cas9-based Chemogenomic Profiling in Mammalian Cells.- 10. Exome Sequencing of Drug-resistant Clones for Target Identification.- 11. The use of large-scale chemically-induced transcriptomedata acquired from LINCS to study small molecules.- 12. Integrated Analysis of Drug Sensitivity and Selectivity to Predict Synergistic Drug Combinations and Target Co-addictions in Cancer.- 13. Predicting Drug Interactions from Chemogenomics using INDIGO.- 14. Computational Analyses Connect Small-Molecule Sensitivity to Cellular Features Using Large Panels of Cancer Cell Lines.- 15. Web-based tools for Polypharmacology Prediction.- 16. In silico Target Prediction for Small Molecules.