Agutter / Taylor The Meaning of Nucleocytoplasmic Transport

Erscheinungsjahr 2013
ISBN: 978-3-662-22502-8
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 200 Seiten, eBook

Reihe: Molecular Biology Intelligence Unit

The means by which proteins and RNAs are exchanged between cytoplasm and nucleus have interested cell biologists for many years, and the field has seen a number of exciting recent advances. Much has been learned about the intricate architecture of the nuclear pore-complex, the mechanisms by which transport substrates are sorted, and the supply of energy for exchange processes. This book attempts a general review of the growing body of knowledge. However, the authors challenge the presumptions implicit in some interpretations of the evidence, re-examining the concept of "transport" within cells, and suggesting that lessons learned from nucleocytoplasmic transport studies can elucidate wider aspects of cell biology.

Zielgruppe

Research

Autoren/Hrsg.

Agutter, Paul S.

Taylor, Philip L.

Inhaltsverzeichnis

1. Perspectives in Transport.- 2. The Vagaries of Diffusion.- 3. Cellular Structures and Nucleocytoplasmic Transport.- 4. Events at the Pore-Complex.- 5. Events Involving the Nucleoskeleton and Cytoskeleton.- 6. Regulation and Pathologies of Nucleocytoplasmic Transport.- 7. Evaluation of a Model.