Bock / Goode Plasminogen-Related Growth Factors

1. Auflage 2008
ISBN: 978-0-470-51547-1
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 268 Seiten, E-Book

Reihe: Novartis Foundation Symposia

A timely volume dealing with the evolutionary and structural links between the clotting and fibrinolytic proteins and plasminogen-related growth factors. The role of individual domains for enzymatic proteins and plasminogen-related growth factors is also comprehensively examined.

Autoren/Hrsg.

Bock, Gregory R.

Goode, Jamie A.

Inhaltsverzeichnis

Evolution of Vertebrate Fibrin Formation and the Process of itsDissolution;
Evolution of Plasminogen-Related Growth Factors and theirReceptors;
Domain Structure and Interactions in Plasminogen;
Structure and Function of Plasminogen: Reconstitution ofMicroplasminogen and Microplasmin from Isolated Fragments;
Protein Engineering of HGF/SF;
Met-HGF/SF: Tumorigenesis, Invasion and Metastasis;
Signalling Through PRGF Receptors;
Plasminogen/Plasmin as a Mediator of ExtracellularProteolysis;
HGF/SF and Met in Chick Development;
Essential Roles of Scatter Factor/Hepatocyte Growth Factor (SF/HGF)and the C-Met Receptor During Mouse Development;
Action of Macrophage-Stimulating Protein (MSP) on Macrophages andKeratinocytes;
HGF/SF in Angiogenesis;
The Organotrophic Function of HGF and its TherapeuticPotential;
Role of SF/Gab-1 in Morphogenesis and Metastasis of MammaryEpithelial Cells.