Boons / Hale Organic Synthesis with Carbohydrates

1. Auflage 2008
ISBN: 978-0-470-76005-5
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 348 Seiten, E-Book

Reihe: Postgraduate Chemistry Series

Carbohydrates offer a ready source of enantiomerically purestarting materials. They have been used for the imaginativesynthesis of a wide range of compounds, and have been found to beeffective chiral auxiliaries which enable the introduction of arange of functionalities in a highly enantioselective manner.
In a subject dominated by volumes at research and professionallevel, this book provides a broad understanding of the use ofcarbohydrates in organic synthesis, at postgraduate student level.Emphasis is placed on retrosynthetic analysis, with discussion ofwhy a particular synthetic route has been chosen, and mechanisticexplanations are provided for key and novel reactions. Whereverpossible, the authors highlight points of general significance toorganic synthesis. Selected experimental conditions and reactiondetails are incorporated to ensure that information can be utilisedin research.
The book is extensively referenced and so provides a convenientpoint of entry to the primary literature.

Autoren/Hrsg.

Boons, Geert-Jan

Hale, Karl J.

Inhaltsverzeichnis

Part A: Structure and Synthesis of Saccharides andGlycoproteins.
1 Mono- and oligosaccharides: structure, configuration andconformation.
2 Protecting groups.
3 Functionalised saccharides.
4 Oligosaccharide synthesis.
5 The chemistry of O- and N-linkedglycopeptides.
Part B: Natural Product Synthesis fromMonosaccharides.
6 (-)-Echinosporin.
7 (+)Zaragozic acid C.
8 (+)-Neocarzinostatin.
9 (+)-Castanospermine.
10 (-)-Silphiperfolene.
11 (-)-Allosamizoline.
12 (-)-Reiswigin A.
13 (-)-Octalactin A.
14 (-)-ACRL toxin I.
15 (+)-Gasbosine E.
16 (-)-Augustamine and (-)-amabiline.
17 (-)-FK506.
18 (3S, 5S)-5-Hydroxypiperazic acid.
References.
Index.