Cagle / Allen / Beasley Precision Molecular Pathology of Lung Cancer

2. Auflage 2018
ISBN: 978-3-319-62941-4
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: Wasserzeichen (»Systemvoraussetzungen)

E-Book, Englisch, 296 Seiten, eBook

Reihe: Molecular Pathology Library

This new edition provides the latest information and insights into the molecular basis for lung cancer. Since the publication of the previous edition of this volume, dramatic changes have occurred with the classification of lung cancer, biomarker testing, and molecular therapy. The book covers these changes, providing updates and new insights on the background of lung cancer, testing methods, and the molecular pathology of specific cell types, including adenocarcinoma, squamous cell carcinoma, small cell carcinoma, and precursor and preinvasive lesions.

Authored by experts in the field,
Precision Molecular Pathology of Lung Cancer, Second Edition
remains one of the few books that comprehensively covers the new molecular pathology of lung cancer and is a valuable resource for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, and thoracic radiologists.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Cagle, Philip T.

Allen, Timothy Craig

Beasley, Mary Beth

Chirieac, Lucian R.

Dacic, Sanja

Borczuk, Alain C.

Kerr, Keith M.

Sholl, Lynette M.

Portier, Bryce

Bernicker, Eric H.

Inhaltsverzeichnis

I. Background.- 1. Precision Medicine of Lung Cancer: Introduction.- 2. Lung Cancer Epidemiology and Demographics.- 3. Genetic Susceptibility to Lung Cancer.- 4. Lung Cancer Stem Cells.- 5. The 2015 World Health Organization Classification of Lung Cancer: Overview.- II. Testing Methods.- 6. Preanalytic considerations.- 7. Mutation testing of lung cancer biomarkers.- 8. Translocation testing of lung cancer biomarkers.- 9. Immunohistochemistry of lung cancer biomarkers.- 10. Next Generation and Third Generation Sequencing of lung cancer biomarkers.- III. Molecular Pathology of Specific Cell Types.- 11. Mutations as Predictive Biomarkers for Adenocarcinoma.- 12. Translocations as predictive Biomarkers for Adenocarcinoma.- 13. Predictive Biomarkers for Squamous Cell Carcinoma.- 14. Molecular Pathology of Small Cell Carcinoma.- 15. Molecular Pathology of Uncommon Carcinomas.- 16. Molecular Pathology of Lung Cancer Metastases.- 17. Molecular Pathology of Precursor and Preinvasive Lesions.- IV. General and Emerging Fields in Molecular Pathology of Lung Cancer.- 18. Prognostic biomarkers in lung cancer.- 19. Biomarkers and Differing Therapy Modalities.- 20. Immuno-oncology of Lung Cancer.- 21. Liquid Biopsy.

Über Autor(innen)

Philip T. Cagle, MDHouston Methodist HospitalDepartment of Pathology & Genomic Medicine6565 Fannin StHouston, TX 77030Timothy C. Allen, MDThe University of Texas Medical Branch Department of Pathology301 University BoulevardGalveston, TX 77555Mary Beth Beasley, MD
Mount Sinai Hospital
Department of Pathology1468 Madison AvenueNew York, NY 10029Lucian R. Chirieac, MDBrigham And Women's HospitalDepartment of Pathology75 Francis St.Boston, MA 02115Sanja Dacic, MD, PhDUniversity of Pittsburgh Medical CenterDepartment of Pathology
200 Lothrop St.
Pittsburgh, PA 15213Alain C. Borczuk, MDWeill Cornell University Medical CenterDepartment of Pathology1300 York AvenueStarr-1000ANew York, NY 10065Keith M. Kerr, MDAberdeen University Medical SchoolAberdeen Royal InfirmaryDepartment of Pathology
Foresterhill
Aberdeen, ScotlandLynette Sholl, MDBrigham And Women's HospitalDepartment of Pathology75 Francis StBoston, MA 02115Bryce Portier, MDHouston Methodist HospitalDepartment of Pathology & Genomic Medicine6565 Fannin StHouston, TX 77030Eric Bern
icker, MD
Houston Methodist HospitalThoracic Medical Oncology6445 Main St, Floor 21Houston, TX 77030