Chader / Greenbaum Artificial Sight

Basic Research, Biomedical Engineering, and Clinical Advances
1. Auflage 2007
ISBN: 978-0-387-49331-2
Verlag: Springer-Verlag
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 400 Seiten

Artificial sight is a frontier area of modern ophthalmology combining the multidisciplinary skills of surgical ophthalmology, biomedical engineering, biological physics, and psychophysical testing. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The goal of is to summarize the state-of-the-art research in this exciting area, and to describe some of the current approaches and initiatives that may help patients in a clinical setting.

The Editors are active researchers in the fields of artificial sight, biomedical engineering and biological physics. They have received numerous professional awards and recognition for their work. The artificial sight team at the Doheny Eye Institute, led by Dr. Mark Humayun, is a world leader in this area of biomedical engineering and clinical research.

Key Features

• Introduces and assesses the state of the art for a broad audience of biomedical engineers, biophysicists, and clinical researchers
• Describes advances in microelectronics, microfabrication, surgical implantation, and psychophysical testing of visual prostheses
• Outlines the promise of artificial sight and the challenges that must be met

Autoren/Hrsg.

Chader, Gerald

Greenbaum, Elias

Inhaltsverzeichnis

1;Series Preface;6
2;Preface;7
3;Contents;8
4;List of Contributors;14
5;List of Acronyms;20
6;Biological Considerations for an Intraocular Retinal Prosthesis;23
7;Artificial Vision: Vision of a Newcomer;52
8;The Effects of Visual Deprivation: Implications for Sensory Prostheses;67
9;Prosthetic Vision Simulation in Fully and Partially Sighted Individuals;91
10;Testing Visual Functions in Patients with Visual Prostheses;111
11;The IMI Retinal Implant System;131
12;Challenges in Realizing a Chronic High- Resolution Retinal Prosthesis;149
13;Large-scale Integration–Based Stimulus Electrodes for Retinal Prosthesis;170
14;Development of a Wireless High- Frequency Microarray Implant for Retinal Stimulation;188
15;Visual Prosthesis Based on Optic Nerve Stimulation with Penetrating Electrode Array;206
16;Dynamic Interactions of Retinal Prosthesis Electrodes with Neural Tissue and Materials Science in Electrode Design;227
17;In Vitro Determination of Stimulus- Induced pH Changes in Visual Prostheses;245
18;Electrochemical Characterization of Implantable High Aspect Ratio Nanoparticle Platinum Electrodes for Neural Stimulations;260
19;High-Resolution Opto-Electronic Retinal Prosthesis: Physical Limitations and Design;272
20;Computational Modeling of Electromagnetic and Thermal Effects for a Dual- Unit Retinal Prosthesis: Inductive Telemetry, Temperature Increase, and Current Densities in the Retina;295
21;Microstimulation with Chronically Implanted Intracortical Electrodes;322
22;A Tissue Change After Suprachoroidal- Transretinal Stimulation with High Electrical Current in Rabbits;339
23;Electrical Stimulation of Mammalian Retinal Ganglion Cells Using Dense Arrays of Small- Diameter Electrodes;347
24;A Mechanism for Generating Precise Temporal Patterns of Activity Using Prosthetic Stimulation;360
25;Electrophysiology of Natural and Artificial Vision;368
26;Index;394