Chadwick / Goode Innate Immunity to Pulmonary Infection

1. Auflage 2007
ISBN: 978-0-470-03538-2
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 238 Seiten, E-Book

Reihe: Novartis Foundation Symposia

Part of the prestigious Novartis Foundation series, this volumeuniquely addresses the use of innate immunity to treat or preventinfectious diseases of the lung.
Innate Immunity to Pulmonary Infection:
* Provides a comprehensive overview of pulmonary infectiousdiseases, including basic pathology, current and potentialtherapies, and detailed consideration of the innate biologicalresistance mechanisms in the lung
* Thoroughly examines the major topic of innate immunity inimmunology, which is now seen as key to the pathogenesis of andvaccination strategies for infectious diseases
* Describes the genetic and environmental factors which determinethe outcome of infection, such as latency of Tuberculosis, bloodstream invasion from local infection, and local target tissuedamage
* Covers the roles of cells such as neutrophils, macrophages anddendritic cells and of molecular components such as Toll-likereceptors
* Discusses the clinical applications of the new knowledgeregarding innate immunity and how this can be used in bothtreatment and prevention (vaccination) strategies
* Includes contributions from an international andinterdisciplinary group of experts
Innate Immunity to Pulmonary Infection is anessential resource for researchers in both industry and academia.It is of interest for all those interested in the disciplines ofimmunology, virology, biology, biotechnology and genetics.

Autoren/Hrsg.

Chadwick, Derek J.

Goode, Jamie A.

Inhaltsverzeichnis

Symposium on Innate immunity to pulmonary infection, held at theWolfson Pavillion, University of Cape Town Medical School, SouthAfrica, 28-30 November 2005.
Editors: Derek J. Chadwick (Organizer) and JamieGoode.
This symposium is based on a proposal made by Siamon Gordon andGordon Brown.
Chair's introduction (Siamon Gordon).
Lung diseases in South Africa: an overview (Eric D.Bateman and Anamika Jithoo).
Discussion.
TB epidemiology and human genetics (Paul D. van Helden, MarloMoller, Chantal Babb, Robin Warren, Gerhard Walzl, Pieter Uysand Eileen Hoal).
Discussion.
Bacterial infections of the lung in normal and immunodeficientpatients (David P. Speert).
Discussion.
Pathogenesis of avian flu H5N1 and SARS (MalikPeiris).
Discussion.
Immunity and tolerance to Aspergillus fumigatus(Claudia Montagnoli, Silvia Bozza, Roberta Gaziano, TeresaZelante, Pierluigi Bonifazi, Francesca Sepioni, Silvia Bellocchio,Lucia Pitzurra and Luigina Romani).
Discussion.
Pentraxins in innate immunity and inflammation (CeciliaGarlanda, Barbara Bottazzi, Giovanni Salvatori, Rita De Santis,Alessia Cotena, Livija Deban, Viriginia Maina, Federica Moalli,Andrea Doni and Alberto Mantovani).
Discussion.
How superoxide production by neutrophil leukocytes killsmicrobes (Anthony W. Segal).
Discussion.
Linking innate to adaptive immunity through dendritic cells(Ralph M. Steinman).
Discussion.
Macrophage receptors and innate immunity: insights from dectin-1(Gordon D. Brown).
Discussion.
Toll-like receptors and control of mycobacterial infection inmice (Bernhard Ryffel, Muazzam Jacobs, Shreemanta Parida, TaniaBotha, Dieudonnée Togbe and ValerieQuesniaux).
Discussion.
Population of lungs by mast cells (T. J. Williams andC. L. Weller).
Discussion.
Innate immunity and mucus structure and function (John K.Sheehan, Mehmet Kesimer and Raymond Pickles).
Discussion.
Collectins and host defence (R. B. Sim, H. Clark, K.Hajelaand K. R. Mayilyan).
Discussion.
Infections and asthma pathogenesis: a critical role fordendritic cells? (Bart N. Lambrecht and Leonie S. vanRijt).
Discussion.
Innate and adaptive immunity in lung cancer (L. A. Vellaand O. J. Finn).
Discussion.
Summing up (Siamon Gordon).
Index of Contributors.
Subject index.

Über Autor(innen)

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.